Prostate cancer trial tests drug holidays to ease treatment burden

NCT ID NCT05884398

Ongoing Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This study is for men with advanced prostate cancer that has spread but still responds to hormone-lowering therapy. After 6 months of successful combination treatment, participants are randomly assigned to either continue hormone therapy or take planned breaks from it. The main goals are to see if taking breaks is just as effective at controlling the cancer and if it reduces the severity of hot flashes, a common and bothersome side effect.

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Contacts and locations

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Locations

Advanced Urology Associates

Joliet, Illinois, 60431, United States
Advanced Urology Institute

Daytona Beach, Florida, 32114, United States
Arizona Urology Specialists

Tucson, Arizona, 85741, United States
Arkansas Urology

Little Rock, Arkansas, 72211, United States
Associated Medical Professionals

Syracuse, New York, 13210, United States
Associated Urological Specialists LLC

Chicago Ridge, Illinois, 60415, United States
CEPHO Centro de Estudos e Pesquisa de Hematologia e Oncologia

Santo André, 09060-650, Brazil
CHU de Quebec Universite Laval Hopital de l Enfant Jesus

Québec, Quebec, G1J 1Z4, Canada
Centers for Advanced Urology LLC d b a MidLantic Urology

Bala-Cynwyd, Pennsylvania, 19004, United States
Central Ohio Urology Group

Gahanna, Ohio, 43230, United States
Centre Leon Berard

Lyon, 69373, France
Centrum Onkologii im Prof F Lukaszczyka

Bydgoszcz, 85 796, Poland
Chesapeake Urology Research Associates

Towson, Maryland, 21204, United States
Chu Rennes Hopital Pontchaillou

Rennes, 35000, France
Colorado Clinical Research

Lakewood, Colorado, 80228, United States
Columbia University Medical Center

New York, New York, 10032, United States
Consultorio de Especialidad en Urologia Privado

Durango, 34000, Mexico
Cuidados Oncologicos

Querétaro, 76000, Mexico
Del Sol Research Management, LLC

Tucson, Arizona, 85715, United States
First Urology, PSC

Jeffersonville, Indiana, 47130, United States
Fundacao Faculdade de Medicina Instituto do Cancer do Estado de Sao Paulo

São Paulo, 01246 000, Brazil
Fundacao Pio XII

Barretos, 14784 400, Brazil
Gustave Roussy

Villejuif, 94805, France
Helios Clinical Research, LLC

Middleburg Heights, Ohio, 44130, United States
Hopital Cochin

Paris, 75014, France
Hospital das Clínicas - Universidade Federal de Minas Gerais

Belo Horizonte, 30130-100, Brazil
Houston Metro Urology

Houston, Texas, 77027, United States
Institut Bergonie

Bordeaux, 33076, France
Instituto D Or de Pesquisa e Ensino

Salvador, 41253 190, Brazil
Klinikum Augsburg

Augsburg, D-86158, Germany
Klinikum rechts der Isar - der Technischen Universität München

München, 81675, Germany
Liga Norte Riograndense Contra O Cancer

Natal, 59062 000, Brazil
MSKCC Basking Ridge

Basking Ridge, New Jersey, 07920, United States
MSKCC Bergen

Montvale, New Jersey, 07645, United States
MSKCC Commack

Commack, New York, 11725, United States
MSKCC Monmouth

Middletown, New Jersey, 07748, United States
MSKCC Nassau Regional Cancer Center

Uniondale, New York, 11553, United States
MSKCC Westchester

Harrison, New York, 10604, United States
Macquarie University Hospital

Macquarie University, 2109, Australia
Maryland Oncology Hematology P A

Silver Spring, Maryland, 20904, United States
Mater Misericordiae Hospital

South Brisbane, 4101, Australia
Medical Care & Research SA de CV

Mérida, 97070, Mexico
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Michigan Institute of Urology

Troy, Michigan, 48084, United States
Ministerio da Saude Instituto Nacional do Cancer

Rio de Janeiro, 20230-130, Brazil
Nanfang Hospital of Southern Medical Hospital

Guangzhou, 510515, China
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy

Warsaw, 02 781, Poland
Ningbo First Hospital

Ningbo, 315010, China
Northwest Cancer Specialists PC

Tigard, Oregon, 97223, United States
Nova Scotia Health Authority

Halifax, Nova Scotia, B3H 2Y9, Canada
Oncology and Hematology Associates of Southwest Virginia, Inc.

Roanoke, Virginia, 98684, United States
Parkland Health and Hospital System

Dallas, Texas, 75235, United States
Peking University First Hospital

Beijing, 100034, China
Peter MacCallum Cancer Centre

Melbourne, 3000, Australia
Polimed Specjalistyczna Przychodnia Lekarska Wieslaw Grazyna Tupikowski Bednarek Tupikowska S C

Wroclaw, 53 329, Poland
Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
SCIENTIA Investigacion Clinica SC

Chihuahua City, 31207, Mexico
Sansum Clinic Pharm

Santa Barbara, California, 93105, United States
Shandong Provincial Hospital

Jinan, 250021, China
Shengjing Hospital Of China Medical University

Shenyang, 110004, China
Southern Alberta Institute of Urology / Prostate Cancer Centre

Calgary, Alberta, T2V 1P9, Canada
Studienpraxis Urologie Nurtingen

Nürtingen, 72622, Germany
Sunnybrook Health Sciences Center

Toronto, Ontario, M4N 3M5, Canada
Szpital Grochowski Im Dr Med Rafala Masztaka Sp Z O O

Warsaw, 04 073, Poland
Szpital Wojewodzki im Mikolaja Kopernika w Koszalinie

Koszalin, 75-581, Poland
Texas Oncology P A

Austin, Texas, 78731, United States
Texas Oncology P A

Dallas, Texas, 75246, United States
Texas Oncology P A

Houston, Texas, 77024, United States
Texas Oncology P A

Wichita Falls, Texas, 76310, United States
Texas Oncology San Antonio Northeast

San Antonio, Texas, 78217, United States
The Conrad Pearson Clinic

Germantown, Tennessee, 38138, United States
The First Affiliated Hospital Sun Yat sen University

Guangzhou, 510080, China
The First Affiliated Hospital of Xian Jiaotong University

Xi'an, 710061, China
The First Hospital of Jilin University

Changchun, 130021, China
TongJi Hospital of TongJi Medical College of Huazhong University of Science & Technology

Wuhan, 430030, China
TriState Urologic Services PSC Inc. DBA The Urology Group

Cincinnati, Ohio, 45212, United States
UT Southwestern Medical Center

Dallas, Texas, 75390, United States
Universitaetsklinikum Carl Gustav Carus TU Dresden

Dresden, 01307, Germany
Universitaetsklinikum Koelnt

Cologne, 50937, Germany
Universitaetsklinikum der RWTH Aachen

Aachen, 52074, Germany
Universitatsklinikum Schleswig Holstein Campus Lubeck

Lübeck, 23538, Germany
Universitatsklinikum Wurzburg

Würzburg, 97080, Germany
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15232, United States
University of Utah Huntsman Cancer Institute

Salt Lake City, Utah, 84112, United States
Urology Associates

Nashville, Tennessee, 37209, United States
Urology Associates of Central California

Fresno, California, 93720, United States
Urology Centers Of Alabama

Homewood, Alabama, 35209, United States
Urology Of Virginia, Pllc

Virginia Beach, Virginia, 23462, United States
Urology of Indiana

Greenwood, Indiana, 46143, United States
VA Medical Center

San Francisco, California, 94121, United States
VA Pittsburgh

Pittsburgh, Pennsylvania, 15240, United States
Virginia Oncology Associates

Norfolk, Virginia, 23502, United States
West China School of Medicine/West China Hospital, Sichuan University

Chengdu, 610041, China

Conditions

Explore the condition pages connected to this study.

METASTATIC CASTRATE-SENSITIVE PROSTATE CANCER