Breathing training may slow muscle decline in ALS patients

NCT ID NCT07413718

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a simple breathing exercise device can help people with ALS maintain the strength of their inspiratory muscles—the muscles that pull air into the lungs. Over 44 participants will do resisted breathing exercises twice daily for 12 weeks, then twice weekly for a year. The goal is to see if this training can slow respiratory decline and improve outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
inspiratory muscle training (a breathing exercise device)
What this could lead to
If it works, this could help people with ALS keep their breathing muscles stronger for longer, potentially improving survival and quality of life.
What could go wrong
This is a small, early-stage trial with only 44 participants. The training may not slow breathing decline enough to make a real difference, and results may not apply to all ALS patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ADELA Gipuzkoa

    RECRUITING

    Donostia / San Sebastian, Gipuzka, 20015, Spain