DNA vaccine shows promise in reducing surgeries for rare throat tumor condition
NCT ID NCT04398433
First seen Apr 16, 2026 · Last updated May 18, 2026 · Updated 5 times
Summary
This study tested a new treatment called INO-3107 for people with recurrent respiratory papillomatosis (RRP), a rare condition where non-cancerous tumors grow in the airway due to HPV-6 or HPV-11. The treatment is a DNA vaccine given with a small electrical pulse to help it enter cells. The main goals were to check safety and see if it could reduce the number of surgeries needed to remove the tumors. The trial included 32 adults and children who required frequent surgeries.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77005, United States
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Cincinnati Children's Hospital
Cincinnati, Ohio, 45229, United States
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Johns Hopkins University School of Medicine
Baltimore, Maryland, 21287, United States
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Mayo Clinic Arizona
Phoenix, Arizona, 85054, United States
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NYU Langone Voice Center
New York, New York, 10016, United States
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UNC School of Medicine
Chapel Hill, North Carolina, 27599, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of California at Davis
Sacramento, California, 95817, United States
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University of Cincinnati Medical Center
Cincinnati, Ohio, 45267, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Winship at Emory University Hospital Midtown
Atlanta, Georgia, 30308, United States
Conditions
Explore the condition pages connected to this study.