Blood-Derived injection may shield teeth from braces damage
NCT ID NCT07352241
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether injecting a substance made from a patient's own blood—called injectable platelet-rich fibrin (i-PRF)—could reduce root shortening that sometimes happens when wearing braces. Thirty-six adults with crowded front teeth received either i-PRF or a saltwater injection during their orthodontic treatment. The goal was to see if i-PRF helps protect the roots of the teeth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
injectable platelet-rich fibrin (i-PRF)
What this could lead to
If it works, this could offer a simple, natural way to protect tooth roots during orthodontic treatment.
What could go wrong
This is a small, early study with only 36 participants, so results may not apply to everyone. The treatment involves injections and may not prevent root damage in all cases.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Orthodontics, Faculty of Dentistry, University of Damsacus
Damascus, DM20 HAJ72, Syria