Blood-Derived injection may shield teeth from braces damage
NCT ID NCT07352241
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether injecting a substance made from a patient's own blood—called injectable platelet-rich fibrin (i-PRF)—could reduce root shortening that sometimes happens when wearing braces. Thirty-six adults with crowded front teeth received either i-PRF or a saltwater injection during their orthodontic treatment. The goal was to see if i-PRF helps protect the roots of the teeth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- injectable platelet-rich fibrin (i-PRF)
- What this could lead to
- If it works, this could offer a simple, natural way to protect tooth roots during orthodontic treatment.
- What could go wrong
- This is a small, early study with only 36 participants, so results may not apply to everyone. The treatment involves injections and may not prevent root damage in all cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CROWDING OF ANTERIOR MAXILLARY TEETH are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Orthodontics, Faculty of Dentistry, University of Damsacus
Damascus, DM20 HAJ72, Syria