Breathing in calm: new sedation method may keep ICU patients Clear-Headed
NCT ID NCT04341350
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to sedate ICU patients who need a breathing machine: inhaled sedation (using isoflurane gas) versus standard intravenous (IV) sedation. The goal is to see if the inhaled approach reduces the chance of delirium—a state of confusion that often occurs in the ICU. About 250 adults on ventilators for at least 24 hours will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH Bourges
Bourges, 18000, France
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CH Corbeil Essonnes
Corbeil-Essonnes, 91106, France
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CH Le Mans
Le Mans, 72039, France
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CH Melun
Melun, 77000, France
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CH Morlaix
Morlaix, 29672, France
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CHU Montpellier
Montpellier, 34295, France
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CHU Poitiers
Poitiers, 86021, France
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CHU Rennes
Rennes, 35033, France
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CHU Tours
Tours, 37044, France
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CHU Tours - Réanimation Chirurgicale
Tours, 37044, France
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CHU de Brest
Brest, 29200, France
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GHBS Lorient
Lorient, 56322, France