Breathing in calm: new sedation method may keep ICU patients Clear-Headed

NCT ID NCT04341350

First seen Jun 17, 2026 · Last updated Jun 17, 2026

Summary

This study compares two ways to sedate ICU patients who need a breathing machine: inhaled sedation (using isoflurane gas) versus standard intravenous (IV) sedation. The goal is to see if the inhaled approach reduces the chance of delirium—a state of confusion that often occurs in the ICU. About 250 adults on ventilators for at least 24 hours will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CH Bourges

    Bourges, 18000, France

  • CH Corbeil Essonnes

    Corbeil-Essonnes, 91106, France

  • CH Le Mans

    Le Mans, 72039, France

  • CH Melun

    Melun, 77000, France

  • CH Morlaix

    Morlaix, 29672, France

  • CHU Montpellier

    Montpellier, 34295, France

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Rennes

    Rennes, 35033, France

  • CHU Tours

    Tours, 37044, France

  • CHU Tours - Réanimation Chirurgicale

    Tours, 37044, France

  • CHU de Brest

    Brest, 29200, France

  • GHBS Lorient

    Lorient, 56322, France

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.