Inhaled drug mist could boost lung cancer treatment before surgery

NCT ID NCT06694454

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 34 times

Summary

This study is for people with early-stage non-small cell lung cancer that can be removed with surgery. Researchers want to see if adding an inhaled form of the drug azacytidine to standard chemotherapy and immunotherapy (durvalumab) before surgery can help kill more cancer cells. About 60 adults will receive the treatment for three 21-day cycles, then have surgery. The goal is to find the safest and most effective dose and to see if the combination leads to no cancer cells left in the removed tissue.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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