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New bone graft could improve spinal fusion for back pain sufferers

NCT ID NCT03118505

Ongoing Disease control Sponsor: Medtronic Spinal and Biologics Source: ClinicalTrials.gov ↗

First seen Jan 13, 2026 · Last updated May 17, 2026 · Updated 12 times

Summary

This study tests a special bone graft (Infuse with Mastergraft) in 100 adults needing spinal fusion for 2-4 levels of the lower back due to conditions like instability or stenosis. The goal is to see if it safely helps bones fuse together better and reduces pain. Participants will be followed for up to 24 months with X-rays and CT scans to check fusion success.

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Contacts and locations

Locations

  • American Neurospine Institute PLLC

    Plano, Texas, 75075, United States

  • Bronson Methodist Hospital

    Kalamazoo, Michigan, 49007, United States

  • Emory University

    Atlanta, Georgia, 30329, United States

  • Fort Wayne Orthopedics

    Fort Wayne, Indiana, 46804, United States

  • Foundation for Orthopedic Research and Education

    Tampa, Florida, 33637, United States

  • Indiana Spine Group

    Carmel, Indiana, 46032, United States

  • New York-Presbyterian Hospital/Columbia University

    New York, New York, 10034, United States

  • Seton Spine & Scoliosis Center

    Austin, Texas, 78731, United States

  • Spine Colorado

    Durango, Colorado, 81301, United States

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • The Spine Health Institute

    Altamonte Springs, Florida, 32701, United States

  • The Steadman Clinic

    Vail, Colorado, 81657, United States

  • The University of Kansas (KUMC)

    Kansas City, Kansas, 66160, United States

  • University of California, Davis

    Sacramento, California, 95816, United States

  • University of Virginia

    Charlottesville, Virginia, 22903, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22903, United States

  • Upstate Orthopedics

    East Syracuse, New York, 13057, United States

Conditions

Explore the condition pages connected to this study.

MULTI-LEVEL DEGENERATIVE LUMBOSACRAL SPINAL CONDITIONS MULTI-LEVEL DEGENERATIVE LUMBOSACRAL SPINAL CONDITIONS