Common painkiller ibuprofen tested as treatment for heart inflammation
NCT ID NCT06686862
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This clinical trial is testing whether a 3-week course of ibuprofen can reduce heart scarring better than standard acetaminophen in people hospitalized with acute myocarditis (heart muscle inflammation). The study will enroll 150 adults with mild cases (normal heart pumping function) and use MRI scans to measure inflammation and scarring over 6 months. If successful, ibuprofen could become a simple, low-cost treatment option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ibuprofen
What this could lead to
If it works, this could provide a simple, widely available treatment to reduce heart scarring in acute myocarditis.
What could go wrong
This is a relatively small Phase 3 trial (150 people) and uses an open-label design, which can introduce bias. Ibuprofen may not outperform acetaminophen, and long-term benefits are uncertain.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MYOCARDITIS ACUTE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Hospital Universitario Puerta de Hierro-Majadahonda
RECRUITINGMajadahonda, Madrid, 28222, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Contact