Experimental drug aims to help kids with genetic short stature grow taller

NCT ID NCT06873035

Summary

This study is testing whether a drug called infigratinib can safely help children with hypochondroplasia, a genetic condition that causes short stature, grow faster and taller. It involves children aged 3 to 18 who have already been in a related observational study. The research will measure changes in annual growth rate, height, body proportions, and safety over time.

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Contacts and locations

Locations

  • Astrid Lindgren Children's Hospital

    Solna, Sweden, 17164, Sweden

  • Centre Hospitalier Universitaire (CHU) de Toulouse - Hôpital des Enfants

    Toulouse, France, 31059, France

  • Children's Hospital of Eastern Ontario Research Institute

    Ottawa, Ontario, K1H 8L1, Canada

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Childrens Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Haukeland University Hospital

    Bergen, Norway, 5021, Norway

  • Hospital Pediátrico de Coimbra

    Coimbra, Portugal, 3000-602, Portugal

  • Hospital Vithas San Jose

    Vitoria-Gasteiz, Spain, 01008, Spain

  • Hôpital Femme Mère Enfant

    Bron, France, 69677, France

  • Hôpital Universitaire Necker-Enfants Malades

    Paris, France, 75015, France

  • Johns Hopkins School of Medicine

    Baltimore, Maryland, 21287, United States

  • KK Women's and Children's Hospital

    Singapore, Singapore, 229899, Singapore

  • London Health Services Center - Children's Hospital of Western Ontario

    London, Ontario, N6C 2R5, Canada

  • Manchester University

    Manchester, United Kingdom, M13 9WL, United Kingdom

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • Paediatric Clinical Research Unit at Osla University Hospital

    Oslo, Norway, 0372, Norway

  • Sheffield Children's Hospital

    Sheffield, United Kingdom, S10 2TH, United Kingdom

  • UCSF Benioff Children's Hospital

    Oakland, California, 94609, United States

  • University of Missouri

    Columbia, Missouri, 65201, United States

  • University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic

    Madison, Wisconsin, 53705, United States

  • Université de Montréal - Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.