Daily pill aims to help kids with dwarfism grow taller and healthier
NCT ID NCT05145010
Summary
This study is testing the long-term safety and effectiveness of a daily oral medication called infigratinib in children with achondroplasia, the most common form of dwarfism. It aims to see if the drug can help children grow taller at a rate closer to average, improve their body proportions, and reduce common health problems. The study is open to children aged 3 to 18 who have growth potential and have either been in a previous related study or meet specific new criteria.
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Contacts and locations
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Locations
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Birmingham Women's and Children's NHS Foundation Trust
Birmingham, B5 6NH, United Kingdom
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Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, H3T 1C5, Canada
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Children's Hospital - London Health Sciences Centre
London, Ontario, N6A 5W9, Canada
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Eastern Ontario
Ottawa, Ontario, K1H 8L1, Canada
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, 20122, Italy
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Haukeland University Hospital
Bergen, 5021, Norway
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Hopital Femme Mere Enfant
Lyon, 69500, France
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Hopital Necker-Enfants Malades
Paris, 75743, France
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Hopital des Enfants
Toulouse, 31300, France
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, 29010, Spain
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Hospital Vithas San José
Vitoria-Gasteiz, Álava, 01012, Spain
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Hospital de Pediatría SAMIC Prof. Dr. Juan P. Garrahan
Ciudad Autonoma Buenos Aires, Buenos Aires, C1245AAM, Argentina
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Johns Hopkins University
Baltimore, Maryland, 21205, United States
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KK Women's and Children's Hosptial
Singapore, 229899, Singapore
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Manchester University Children's Hospital
Manchester, M13 9WL, United Kingdom
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Murdoch Children's Hospital
Parkville, Victoria, 3052, Australia
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Nemours Alfred I. Dupont Hospital for Children
Wilmington, Delaware, 19803, United States
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Oslo University Hospital
Oslo, 0372, Norway
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Policlinico A. Gemelli IRCCS
Roma, 00168, Italy
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Queen Elizabeth University Hospital
Glasgow, G12 0XH, United Kingdom
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Sheffield Children's Hospital
Sheffield, S10 2TH, United Kingdom
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St. Thomas' Hospital
London, SE1 7EH, United Kingdom
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Stollery Children's Hospital
Edmonton, Alberta, T6C 2B7, Canada
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USCF Benioff Children's Hospital, Oakland
Oakland, California, 94609, United States
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University Hospital and UW Health Clinics
Madison, Wisconsin, 53705, United States
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University Hospitals Bristol and Weston NHS Foundation Trust
Bristol, BS2 8AE, United Kingdom
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University of Missouri
Columbia, Missouri, 65212, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.