New drug trial aims to protect kids from inherited heart risk

NCT ID NCT06597019

Summary

This study is testing a drug called inclisiran to see if it safely lowers bad cholesterol in children aged 6 to 12 who have an inherited condition causing very high cholesterol. For the first year, some children will receive the drug and others a placebo, followed by a year where all children receive the drug. The goal is to control this lifelong condition early to help prevent future heart problems.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Children's National Hospital

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Childrens National Hospital

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-••••

    Contact

  • Excel Medical Clinical Trials LLC

    RECRUITING

    Boca Raton, Florida, 33434, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Icahn School of Med at Mt Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Novartis Investigative Site

    RECRUITING

    Buenos Aires, C1245AAM, Argentina

  • Novartis Investigative Site

    RECRUITING

    CABA, C1181ACH, Argentina

  • Novartis Investigative Site

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    Salzburg, 5020, Austria

  • Novartis Investigative Site

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    Vienna, 1090, Austria

  • Novartis Investigative Site

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    Brussels, 1200, Belgium

  • Novartis Investigative Site

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    Leuven, 3000, Belgium

  • Novartis Investigative Site

    RECRUITING

    Fortaleza, Ceará, 60430-275, Brazil

  • Novartis Investigative Site

    RECRUITING

    Rio de Janeiro, Rio de Janeiro, 20211-340, Brazil

  • Novartis Investigative Site

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90020-020, Brazil

  • Novartis Investigative Site

    RECRUITING

    São Paulo, São Paulo, 05403 000, Brazil

  • Novartis Investigative Site

    RECRUITING

    Beijing, Beijing Municipality, 100013, China

  • Novartis Investigative Site

    RECRUITING

    Shanghai, 200127, China

  • Novartis Investigative Site

    RECRUITING

    Prague, 128 08, Czechia

  • Novartis Investigative Site

    RECRUITING

    Prague, 150 06, Czechia

  • Novartis Investigative Site

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    Marseille, 13885, France

  • Novartis Investigative Site

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    Nantes, 44093, France

  • Novartis Investigative Site

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    Paris, 75012, France

  • Novartis Investigative Site

    RECRUITING

    Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany

  • Novartis Investigative Site

    RECRUITING

    Frankfurt am Main, Hesse, 60590, Germany

  • Novartis Investigative Site

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    Hanover, 30173, Germany

  • Novartis Investigative Site

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    Athens, 115 27, Greece

  • Novartis Investigative Site

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    Ioannina, 455 00, Greece

  • Novartis Investigative Site

    RECRUITING

    Hong Kong, 999077, Hong Kong

  • Novartis Investigative Site

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    Budapest, 1026, Hungary

  • Novartis Investigative Site

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    Jerusalem, 9112001, Israel

  • Novartis Investigative Site

    RECRUITING

    Ramat Gan, 5265601, Israel

  • Novartis Investigative Site

    RECRUITING

    Milan, MI, 20162, Italy

  • Novartis Investigative Site

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    Roma, RM, 00165, Italy

  • Novartis Investigative Site

    RECRUITING

    Torino, TO, 10126, Italy

  • Novartis Investigative Site

    RECRUITING

    Verona, VR, 3712, Italy

  • Novartis Investigative Site

    RECRUITING

    Kuala Lumpur, Kuala Lumpur, 50586, Malaysia

  • Novartis Investigative Site

    RECRUITING

    Amsterdam, North Holland, 1105 AZ, Netherlands

  • Novartis Investigative Site

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    Bialystok, 15-274, Poland

  • Novartis Investigative Site

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    Gdansk, 80 952, Poland

  • Novartis Investigative Site

    RECRUITING

    Lodz, Łódź Voivodeship, 93-338, Poland

  • Novartis Investigative Site

    RECRUITING

    Coimbra, 3000-602, Portugal

  • Novartis Investigative Site

    RECRUITING

    Lisbon, 1649-035, Portugal

  • Novartis Investigative Site

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    Porto, 4050-651, Portugal

  • Novartis Investigative Site

    RECRUITING

    Porto, 4200 319, Portugal

  • Novartis Investigative Site

    RECRUITING

    Bloemfontein, Free State, 9301, South Africa

  • Novartis Investigative Site

    RECRUITING

    Elche, Alicante, 03203, Spain

  • Novartis Investigative Site

    RECRUITING

    Cadiz, Andalusia, 11009, Spain

  • Novartis Investigative Site

    RECRUITING

    Esplugues, Barcelona, 08950, Spain

  • Novartis Investigative Site

    RECRUITING

    Badalona, Catalonia, 08916, Spain

  • Novartis Investigative Site

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Novartis Investigative Site

    RECRUITING

    Barcelona, 08041, Spain

  • Novartis Investigative Site

    RECRUITING

    Málaga, 29011, Spain

  • Novartis Investigative Site

    RECRUITING

    Seville, 41013, Spain

  • Novartis Investigative Site

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    Taipei, 111045, Taiwan

  • Novartis Investigative Site

    RECRUITING

    Taipei, 11217, Taiwan

  • Novartis Investigative Site

    RECRUITING

    Adana, Saricam, 01330, Turkey (Türkiye)

  • Novartis Investigative Site

    RECRUITING

    Ankara, Yenimahalle, 06500, Turkey (Türkiye)

  • Novartis Investigative Site

    RECRUITING

    Izmir, 35100, Turkey (Türkiye)

  • Novartis Investigative Site

    RECRUITING

    West Midlands, Birmingham, B4 6NH, United Kingdom

  • Novartis Investigative Site

    RECRUITING

    London, NW3 2QG, United Kingdom

  • Primary Childrens Medical Center

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84113, United States

  • Primary Childrens Medical Center

    RECRUITING

    Salt Lake City, Utah, 84113, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact

    Contact Email: •••••@•••••

  • UC San Francisco Medical Center

    RECRUITING

    San Francisco, California, 94143, United States

  • UC San Francisco Medical Center

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact

    Contact Email: •••••@•••••

  • West Virginia Childrens Hospital

    RECRUITING

    Morgantown, West Virginia, 26506, United States

  • West Virginia Childrens Hospital

    RECRUITING

    Morgantown, West Virginia, 26506, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.