New drug INCB160058 enters early human testing for rare blood cancers

NCT ID NCT06313593

Recruiting now Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Nov 05, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This early-stage study tests a new drug, INCB160058, in 186 adults with myeloproliferative neoplasms (a group of blood cancers). The main goal is to check the drug's safety and how the body processes it. Participants must be 18 or older and meet specific disease criteria, including prior treatment for some forms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Aou Policlinico S. Orsola-Malpighi
NOT_YET_RECRUITING

Bologna, 40138, Italy
Azienda Ospedaliero-Universitaria Careggi (Aouc)
NOT_YET_RECRUITING

Florence, 50134, Italy
Cornell Medical Center
RECRUITING

New York, New York, 10021, United States
Fondazione Irccs Ca Granda Ospedale Maggiore
NOT_YET_RECRUITING

Milan, 20122, Italy
Genesiscare Oxford
NOT_YET_RECRUITING

Oxford, OX4 6LB, United Kingdom
Guys and St Thomas Nhs Foundation Trust
NOT_YET_RECRUITING

London, SE1 9RT, United Kingdom
Haukeland University Hospital
RECRUITING

Bergen, N-5021, Norway
Hopital Maisonneuve-Rosemont, Montreal, Qc
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
Hospital Saint Louis
RECRUITING

Paris, 75010, France
Icahn School of Medicine At Mount Sinai
RECRUITING

New York, New York, 10029, United States
Inselspital - Universitaetsspital Bern
RECRUITING

Bern, 03010, Switzerland
Institut Gustave Roussy
RECRUITING

Villejuif, 94805, France
McGill University Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Oregon Health & Science University
RECRUITING

Portland, Oregon, 97239, United States
Oslo University Hospital
RECRUITING

Oslo, 00379, Norway
Princess Margaret Cancer Center
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Sloan Kettering Institute For Cancer Research
RECRUITING

New York, New York, 10065, United States
Stanford University
RECRUITING

Palo Alto, California, 94304, United States
The University of Alabama At Birmingham
RECRUITING

Birmingham, Alabama, 35249, United States
The University of Kansas Cancer Center Kucc University of Kansas Clinical Research Center
RECRUITING

Fairway, Kansas, 66205, United States
Universitatsklinikum Essen
NOT_YET_RECRUITING

Essen, 45147, Germany
Universitatsklinikum Halle (Saale)
RECRUITING

Halle, 06120, Germany
Universitatsspital Zurich
RECRUITING

Zurich, 08091, Switzerland
University Medical Center Rwth Aachen
RECRUITING

Aachen, D-52074, Germany
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109-5008, United States
University of Pennsylvania Health System
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Vanderbilt-Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.

MYELOPROLIFERATIVE NEOPLASMS MYELOPROLIFERATIVE NEOPLASMS