New drug tested for tough bone cancer after other treatments fail

NCT ID NCT03514407

Summary

This early-stage study tested the safety and initial effects of an experimental drug called INCB059872 in 25 people with advanced Ewing sarcoma, a rare bone and soft tissue cancer. Participants had cancer that returned or didn't respond to standard treatments and had no other curative options. The main goal was to see how well the drug was tolerated and if it showed any signs of shrinking tumors.

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Contacts and locations

Locations

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Hospital Clínico San Carlos

    Madrid, 28040, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Istituto Ortopedico Rizzoli

    Bologna, 40136, Italy

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic Jacksonville - PPDS

    Jacksonville, Florida, 32224, United States

  • Ospedale Pediatrico Bambino Gesu IRCCS

    Rome, 00146, Italy

  • Policlinico Sant'orsola-Malpighi

    Bologna, 40138, Italy

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • UCLA Jonsson Comprehensive Cancer

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.