New drug combo tested in fight against tough cancers
NCT ID NCT04989387
Summary
This early-stage study tested a new drug called INCA00186, given alone or combined with other immunotherapy drugs, in people with advanced head/neck cancers or certain gastrointestinal cancers. The main goals were to check the safety of the drug, find the right dose, and see if it showed any early signs of helping to control the cancer. The study specifically looked for people whose tumors had a certain type of immune cell, hoping they might respond better to this kind of treatment.
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Contacts and locations
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Locations
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Cambridge University Hospitals Nhs Foundation Trust
Cambridge, CB2 0QQ, United Kingdom
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Carolina Bio-Oncology Institute, Pllc
Huntersville, North Carolina, 28078, United States
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Cliniques Universitaires Ucl Saint-Luc
Brussels, 01200, Belgium
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Emory University
Atlanta, Georgia, 30322, United States
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Erasmus Mc Cancer Institute
Rotterdam, 3015GD, Netherlands
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Freeman Hospital Newcastle Upon Tyne Foundation Nhs Trust
Newcastle upon Tyne, NE7 7DN, United Kingdom
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Fundacion Jimenez Diaz University Hospital
Madrid, 28040, Spain
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Ghent University Hospital
Ghent, 09000, Belgium
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Guys and St Thomas Nhs Foundation Trust
London, SE1 9RT, United Kingdom
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Hospital Clinico Universitario Virgen de La Victoria
Málaga, 29010, Spain
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Hospital General Universitario Vall D Hebron
Barcelona, 08035, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario Quironsalud Madrid
Pozuelo de Alarcón, 28223, Spain
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Imperial College Healthcare Nhs Trust - Hammersmith Hospital
London, W12 0HS, United Kingdom
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Innsbruck University Hospital
Innsbruck, A-6020, Austria
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Institut Catala Doncologia Ico - Hospital Duran I Reynals Location
Barcelona, 199203, Spain
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Institut Jules Bordet
Brussels, B-1070, Belgium
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Landeskrankenhaus Salzburg
Salzburg, 05020, Austria
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Md Anderson Cancer Center
Houston, Texas, 77030, United States
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Netherlands Cancer Institute Antoni Van Leeuwenhoek Ziekenhuis
Amsterdam, 1066 CX, Netherlands
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Radboud University Nijmegen Medical Center
Nijmegen, 6525 GA, Netherlands
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South Texas Accelerated Research Therapeutics
San Antonio, Texas, 78229, United States
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The Angeles Clinic and Research Institute
Los Angeles, California, 90025, United States
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The Christie Nhs Foundation Trust Uk
Manchester, M20 4BV, United Kingdom
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The Royal Marsden Nhs Foundation Trust - Chelsea
Sutton, SM2 5PT, United Kingdom
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Universitair Ziekenhuis (Uz) Leuven
Leuven, 03000, Belgium
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Universitair Ziekenhuis Antwerpen (Uza)
Edegem, 02650, Belgium
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University Medical Center Groningen
Groningen, 9713GZ, Netherlands
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University Medical Center Utrecht
Utrecht, 3584 CX, Netherlands
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University of Maryland-Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States
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Vanderbilt Medical Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.