New trial aims to find best treatment for returning leukemia

NCT ID NCT06713837

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 32 times

Summary

This study tests whether a gentler, low intensity therapy works better than strong chemotherapy for people whose acute myeloid leukemia (AML) has come back or not responded to treatment. About 339 adults with AML in their first or second relapse will be randomly assigned to one of the two approaches. The goal is to see which treatment helps patients live longer without the cancer worsening.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A. O. Ordine Mauriziano

    RECRUITING

    Torino, TO, 10128, Italy

    Contact

  • AOU Careggi

    RECRUITING

    Florence, 50019, Italy

    Contact

  • AOU Città della Salute e della Scienza di Torino

    RECRUITING

    Torino, TO, 10126, Italy

    Contact

  • ASST Grande Ospedale Metropolitano Niguarda

    NOT_YET_RECRUITING

    Milan, 20162, Italy

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  • ASST Valle Olonda

    RECRUITING

    Busto Arsizio, 21052, Italy

    Contact

  • ASST degli Spedali Civili

    RECRUITING

    Brescia, 25123, Italy

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  • Azienda Ospedale-Università Padova

    RECRUITING

    Padova, 35100, Italy

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  • Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli

    NOT_YET_RECRUITING

    Naples, 80131, Italy

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  • Azienda Ospedaliero Universitaria Delle Marche

    NOT_YET_RECRUITING

    Ancona, 60126, Italy

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  • Azienda Ospedaliero-Universitaria Senese

    NOT_YET_RECRUITING

    Siena, 53100, Italy

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  • Azienda Unita Sanitaria Locale Di Piacenza

    NOT_YET_RECRUITING

    Piacenza, 29121, Italy

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  • Casa Sollievo Della Sofferenza

    NOT_YET_RECRUITING

    San Giovanni Rotondo, 71013, Italy

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  • Consorcio Hospital General Universitario De Valencia

    NOT_YET_RECRUITING

    Valencia, 46014, Spain

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  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, 20122, Italy

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  • Fondazione IRCCS Policlinico San Matteo

    NOT_YET_RECRUITING

    Pavia, 27100, Italy

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  • Fundeni Clinical Institute

    RECRUITING

    Bucharest, 022328, Romania

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  • Heinrich-Braun-Klinikum gGmbH

    NOT_YET_RECRUITING

    Zwickau, 08060, Germany

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  • Hospital Clinico Universitario De Valencia

    NOT_YET_RECRUITING

    Valencia, 46010, Spain

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  • Hospital General Universitario De Albacete

    NOT_YET_RECRUITING

    Albacete, 02006, Spain

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  • Hospital General Universitario Dr. Balmis

    NOT_YET_RECRUITING

    Alicante, 03010, Spain

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  • Hospital Universitari Vall D Hebron

    NOT_YET_RECRUITING

    Barcelona, 08035, Spain

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  • Hospital de Santa Maria

    RECRUITING

    Lisbon, 1649-035, Portugal

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  • IRCCS Ospedale Policlinico San Martino

    NOT_YET_RECRUITING

    Genova, GE, 16132, Italy

  • IRCCS Ospedale Policlinico San Martino

    NOT_YET_RECRUITING

    Genova, GE, 16132, Italy

    Contact

    Contact

  • IRST Istituto Romagnolo per lo Studio dei Tumori Dino Amadori

    RECRUITING

    Meldola, 47014, Italy

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  • Instituto de Investigación Sanitaria La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact

  • Istituto Oncologico Veneto IRCCS

    RECRUITING

    Castelfranco Veneto, 31033, Italy

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  • Krankenhaus St. Elisabeth und St. Barbara Halle (Saale) GmbH

    NOT_YET_RECRUITING

    Halle, 06110, Germany

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  • Ospedale Infermi

    RECRUITING

    Rimini, 47923, Italy

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  • Ospedale S.Spirito - ASL Pescara

    NOT_YET_RECRUITING

    Pescara, PE, 65124, Italy

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  • Ospedale San Bortolo

    RECRUITING

    Vicenza, 36100, Italy

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  • Ospedale Santa Maria della Misericordia

    RECRUITING

    Perugia, PG, 06156, Italy

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  • Ospedale Santa Maria delle Croci

    RECRUITING

    Ravenna, RA, 48121, Italy

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  • Ospedali Riuniti Villa Sofia - Cervello

    RECRUITING

    Palermo, PA, 90146, Italy

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  • Policlinico Sant'Orsola

    RECRUITING

    Bologna, BO, 40138, Italy

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  • Policlinico Tor Vergata

    RECRUITING

    Roma, RM, 00133, Italy

    Contact

  • Policlinico Umberto I

    RECRUITING

    Roma, RM, 00161, Italy

    Contact

  • The Hospital of Lithuanian University of Health Sciences Kauno Klinikos

    RECRUITING

    Kaunas, 50161, Lithuania

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  • Uniklinik RWTH Aachen

    RECRUITING

    Aachen, 52074, Germany

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  • University Hospital Brno

    RECRUITING

    Brno, 625 00, Czechia

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  • University Hospital Greifswald

    RECRUITING

    Greifswald, 17475, Germany

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  • University Hospital Halle

    RECRUITING

    Halle, 06120, Germany

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  • University Hospital Hradec Králové

    NOT_YET_RECRUITING

    Hradec Králové, 500 05, Czechia

    Contact

  • University Hospital Olomouc

    NOT_YET_RECRUITING

    Olomouc, 779 00, Czechia

    Contact

  • University Hospital in Ostrava

    NOT_YET_RECRUITING

    Ostrava, 708 00, Czechia

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  • University Hospital in Pilsen

    NOT_YET_RECRUITING

    Pilsen, 323 00, Czechia

    Contact

  • University Hospital of Rostock

    RECRUITING

    Rostock, 18507, Germany

    Contact

Conditions

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