Immunotherapy combo shows promise for stage III lung cancer

NCT ID NCT03285321

First seen Jan 24, 2026 · Last updated Jun 15, 2026 · Updated 21 times

Summary

This study tested whether adding immunotherapy drugs (nivolumab alone or with ipilimumab) after standard chemoradiation helps people with stage III non-small cell lung cancer that cannot be removed by surgery. 105 participants were randomly assigned to one of two treatment groups. The main goal was to see how long the cancer stayed under control. This is a disease control approach, not a cure, as ongoing monitoring and treatment may be needed.

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Contacts and locations

Locations

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Johns Hopkins Sidney Kimmel Comprehensive

    Baltimore, Maryland, 21287, United States

  • Karmanos Cancer Center (Wayne State University)

    Detroit, Michigan, 48201, United States

  • Michigan State University

    Lansing, Michigan, 48910, United States

  • Penn State Cancer Institute

    Hershey, Pennsylvania, 17033, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Illinois Cancer Center

    Chicago, Illinois, 60612, United States

  • University of Louisville James Graham Brown Cancer Center

    Louisville, Kentucky, 40202, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Wisconsin

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.