New drug combo aims to shrink tumors before surgery in Hard-to-Treat rectal cancer

NCT ID NCT07160647

Summary

This study is testing whether giving two immunotherapy drugs (iparomlimab and tuvonralimab) before surgery can help shrink or eliminate tumors in patients with a specific type of locally advanced rectal cancer. The main goal is to see if the treatment leads to a 'pathologic complete response,' meaning no cancer cells are found in the surgical specimen. Researchers will also closely monitor side effects and quality of life.

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Contacts and locations

Locations

  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine,

    Hangzhou, Zhejiang, 310016, China

Conditions

Explore the condition pages connected to this study.