New hope for Tough-to-Treat breast cancer: multiple drug combos tested

NCT ID NCT03280563

Summary

This study tested several immunotherapy-based drug combinations for people with advanced HR-positive, HER2-negative breast cancer that had worsened despite standard hormone therapy. It involved 144 participants who received different combinations of drugs, including a standard hormone therapy as a comparison. The goal was to see which combinations could best shrink tumors and control the cancer while monitoring side effects.

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Contacts and locations

Locations

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

  • Levine Cancer Institute

    Charlotte, North Carolina, 28204, United States

  • Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center

    Torrance, California, 90502, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cancer Center

    Gyeonggi-do, 10408, South Korea

  • Northwest Georgia Oncology Centers PC - Marietta

    Marietta, Georgia, 30060, United States

  • Providence Cancer Center

    Portland, Oregon, 97231, United States

  • Rabin Medical Center-Beilinson Campus

    Petah Tikva, 4941492, Israel

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Sarah Cannon Research Institute / Tennessee Oncology

    Nashville, Tennessee, 37203, United States

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Shaare Zedek Medical Center

    Jerusalem, 9103102, Israel

  • Sheba Medical Center

    Ramat Gan, 5262100, Israel

  • Stanford Cancer Institute

    Stanford, California, 94305-5456, United States

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, 64239, Israel

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • UCSF Helen Diller Family CCC

    San Francisco, California, 94158, United States

  • UPMC Pinnacle Health System

    Harrisburg, Pennsylvania, 17102, United States

  • Univ of Pittsburgh Sch of Med

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

  • University of Ulsan College of Medicine - Asan Medical Center

    Seoul, 05505, South Korea

  • Wellness Oncology and Hematology - Main Office

    West Hills, California, 91307, United States

Conditions

Explore the condition pages connected to this study.