Blood cancer breakthrough: new therapy may stop deadly infections after CAR-T treatment
NCT ID NCT05952804
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 24 times
Summary
This study tests whether giving antibody replacements can prevent serious infections in people who have received CAR-T therapy for blood cancers. CAR-T therapy often lowers the body's natural antibodies, raising infection risk. The trial will compare antibody replacement to a placebo in 150 patients to see if it reduces bacterial infections.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Cancer Center
RECRUITINGDuarte, California, 91010, United States
Contact
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Fred Hutch/University of Washington Cancer Consortium
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Massachusetts General Hospital Cancer Center
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact
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Oregon Health and Science University (OHSU) Knight Cancer Institute
RECRUITINGPortland, Oregon, 97239, United States
Contact
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University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
Contact
Conditions
Explore the condition pages connected to this study.