Lymphoma Patients' vaccine response under scrutiny

NCT ID NCT05050461

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 22 times

Summary

This study looked at how the COVID-19 vaccine triggers an immune response in adults with B-cell non-Hodgkin lymphoma, especially those recently treated with anti-CD20 drugs. Researchers compared antibody and T-cell levels between patients who had anti-CD20 therapy in the past year and those who did not. The goal was to understand if these treatments weaken vaccine protection. The study was terminated early, but it aimed to help guide future vaccine and treatment recommendations for this vulnerable group.

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Contacts and locations

Locations

  • André Mignot -Versailles Hospital, Hemato-oncology unit

    Le Chesnay, Île-de-France Region, 78150, France

  • Emile Muller Hospital, Hematology unit

    Mulhouse, 68100, France

  • Hospitals of Brabois, Hematology unit

    Vandœuvre-lès-Nancy, 54500, France

  • Institut of Cancerology Strasbourg Europe (ICANS), Hematology deparment

    Strasbourg, 67000, France

  • Pitié Salpêtrière Hospital, Hematology unit

    Paris, Île-de-France Region, 75013, France

  • Saint Antoine Hospital, Hematology unit

    Paris, Île-de-France Region, 75012, France

  • saint Louis Hospital, Hemato-oncology unit

    Paris, Île-de-France Region, 75010, France

Conditions

Explore the condition pages connected to this study.