New hope for rare gaucher type III: high-dose enzyme therapy shows promise

NCT ID NCT04656600

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 30 times

Summary

This study looked at whether a higher dose of the drug imiglucerase can safely improve blood counts, reduce organ swelling, and ease bone pain in Chinese patients with Gaucher disease type III. Twelve patients over age 2 received the maximum approved dose for one year. The goal was to control the disease and improve quality of life, not to cure it.

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Contacts and locations

Locations

  • Investigational Site Number : 101

    Beijing, 100032, China

  • Investigational Site Number : 102

    Guangzhou, 510080, China

  • Investigational Site Number : 104

    Chengdu, 610041, China

  • Investigational Site Number : 105

    Guangzhou, 510623, China

  • Investigational Site Number : 107

    Beijing, 100020, China

Conditions

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