Eye scan may spot hidden nerve pain in dry eye sufferers

NCT ID NCT05653921

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This study aims to see if a special microscope (confocal microscopy) can reliably detect tiny nerve growths (microneuromas) that cause neuropathic corneal pain. Researchers will scan the eyes of 438 adults with dry eye or corneal disease to confirm if these nerve findings are a dependable diagnostic tool. The goal is to improve diagnosis of this often-missed pain condition.

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Contacts and locations

Locations

  • Scheie Eye Institute, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

Conditions

Explore the condition pages connected to this study.