New hope for myelofibrosis patients with anemia: drug combo targets spleen and symptoms
NCT ID NCT07447817
First seen Mar 21, 2026 · Last updated Apr 29, 2026 · Updated 7 times
Summary
This study tests two drugs, selinexor and pacritinib, in people with myelofibrosis who have not had JAK inhibitor treatment and have low red blood cells (anemia) and low platelets (thrombocytopenia). The goal is to see if the combination can shrink the spleen and improve symptoms. About 26 adults will take part in this early-phase trial.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
Contact
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The University of Kansas Cancer Center-Westwood
Westwood, Kansas, 66205, United States
Contact
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Wake Forest Baptist Health Comprehensive Cancer Center
Winston-Salem, North Carolina, 27157, United States
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Conditions
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