Can IL-2 keep HIV patients healthier without antiretrovirals?

NCT ID NCT00120185

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether interleukin-2 (IL-2) can help maintain CD4 cell counts in people with HIV who have not yet started antiretroviral therapy. 130 participants with CD4 counts between 300 and 500 will receive IL-2 injections. The goal is to see if IL-2 can delay the need for standard HIV medications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Interleukin-2 (IL-2)
What this could lead to
If successful, this could show that IL-2 helps delay the need for antiretroviral therapy in early HIV infection.
What could go wrong
This is a small, early-phase trial with only 130 participants. IL-2 may not prevent CD4 decline, and side effects are possible. Results may not apply to all HIV patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service des Maladies Infectieuses

    Paris, 75010, France

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Other studies related to the condition(s) this trial covers.