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Does a neck line raise brain pressure? small study uses eye ultrasound to find out

NCT ID NCT07465419

Knowledge-focused Sponsor: Cumhuriyet University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether inserting a central line into the neck vein affects brain pressure in 50 ICU patients on breathing machines. Doctors used ultrasound to measure the nerve sheath at the back of the eye before and after the procedure. The goal was to see if this simple method could detect any pressure changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand whether placing a central line in the neck safely affects brain pressure in ICU patients.
What could go wrong
This is a small, completed observational study with only 50 participants. It does not test a treatment, so it cannot directly lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Feb 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Intubated intensive care unit patients who receive internal jugular vein catheterization

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The study will include adult patients over 18 years of age who are on mechanical ventilation support and monitored in the intensive care unit. Exclusion Criteria: * patients with intracranial tumors * patients with acute traumatic brain injury * patients diagnosed with acute or chronic eye diseases * hypercarbic patients * Patients receiving inotropic support * patients using medications that affect intraocular pressure

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intracranial pressure measurement Measurement of optic nerve sheath diameter

Contacts and locations

Locations

  • Sivas Cumhuriyet University

    Sivas, Sivas, 58140, Turkey (Türkiye)