New drug trial aims to protect kidneys from devastating autoimmune disease

NCT ID NCT05797610

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug called sefaxersen can slow kidney damage in people with IgA nephropathy who are at high risk of their disease getting worse. Researchers will compare the drug to a placebo in 428 participants over about two years to see if it reduces protein in urine and protects kidney function. The goal is to control the disease and delay or prevent kidney failure.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

4. Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 53-114, Poland
Academic Medical Research Institute - Los Angeles
RECRUITING

Los Angeles, California, 90022, United States
Addenbrookes Hospital
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Affiliated Hospital of Jiangsu University
RECRUITING

Zhenjiang, 212001, China
Ajou University Hospital
RECRUITING

Gyeonggi-do, 443-380, South Korea
Alabama Kidney Research - ERN - PPDS
RECRUITING

Alabaster, Alabama, 35007-8823, United States
Austin Diagnostic Clinic - Frenova F1
RECRUITING

Austin, Texas, 78751-3014, United States
Azienda Ospedaliera Universitaria Federico II
RECRUITING

Naples, Campania, 80131, Italy
Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
RECRUITING

Bari, Apulia, 70124, Italy
Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi-Via Massarenti
RECRUITING

Bologna, Emilia-Romagna, 40138, Italy
Beijing Friendship Hospital, Capital Medical University - PPDS
RECRUITING

Beijing, Beijing Municipality, 000000, China
C.H. Regional Reina Sofia - PPDS
RECRUITING

Córdoba, 14004, Spain
CHA Bundang Medical Center, CHA University
RECRUITING

Seongnam-si, 13496, South Korea
CHU Boulogne sur Mer
RECRUITING

Boulogne-sur-Mer, 62200, France
Cangzhou Central Hospital
RECRUITING

Cangzhou Shi, Hebei, 060001, China
Cape Breton Regional Hospital
RECRUITING

Sydney, Nova Scotia, B1P 1P3, Canada
Care Institute Idaho Kidney Institute
RECRUITING

Chubbuck, Idaho, 83202, United States
Care Institute Idaho Kidney Institute
RECRUITING

Idaho Falls, Idaho, 83402, United States
Central Florida Kidney Specialists
RECRUITING

Orlando, Florida, 32806, United States
Centre Hospitalier
RECRUITING

Annonay, 07103, France
Centre Hospitalier Universitaire de Quebec
RECRUITING

Québec, G1R 2J6, Canada
Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada
RECRUITING

Ciudad Autonoma Buenos Aires, C1425AGC, Argentina
Centro de Investigacion Clinica Chapultepec S. A. de C. V.
RECRUITING

Morelia, Michoacán, 58260, Mexico
Centro de Pesquisa Clinica da Fundação Pró Rim
RECRUITING

Joinville, Santa Catarina, 89227-680, Brazil
Chang Gung Medical Foundation
RECRUITING

Kaohsiung City, 83301, Taiwan
Chang Gung Memorial Hospital, Linkou
RECRUITING

Taoyuan, 333, Taiwan
Changhua Christian Hospital
RECRUITING

Changhua, 500, Taiwan
Changi General Hospital
RECRUITING

Singapore, 529889, Singapore
Changzhou First People's Hospital
RECRUITING

Changzhou, 213003, China
China Medical University Hospital
RECRUITING

Taichung, 40447, Taiwan
Christus Latam Hub Center Of Excellence & Innovation
RECRUITING

Monterrey, Nuevo León, 64000, Mexico
Chungbuk National University Hospital
RECRUITING

Cheongju-si, 28644, South Korea
Churchill Hospital
RECRUITING

Oxford, OX3 7LE, United Kingdom
Clinica San Cosme
RECRUITING

Fracc Lomas Del Campestre, Aguascalientes, 20129, Mexico
Consultorios Médicos Dr. Doreski
RECRUITING

Ciudad Autonoma Buenos Aires, C1426ABP, Argentina
Cowry Medical Group LLC
RECRUITING

Acworth, Georgia, 30101, United States
Faculdade de Medicina da Universidade de Sao Paulo
RECRUITING

São Paulo, São Paulo, 01246, Brazil
Fakultni nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 05, Czechia
Far Eastern Memorial Hospital
RECRUITING

Taipei, 220, Taiwan
Fondazione Policlinico Universitario A Gemelli
RECRUITING

Rome, Lazio, 00168, Italy
Freire Pesquisa Clinica
RECRUITING

Belo Horizonte, Minas Gerais, 30150, Brazil
Fujita Health University Hospital
RECRUITING

Aichi, 470-1192, Japan
Gangdong Kyung Hee University Hospital
RECRUITING

Seoul, 05278, South Korea
General Hospital of Ningxia Medical University
RECRUITING

Yinchuan, 750004, China
Global Medical Research - M3 WR
WITHDRAWN

Dallas, Texas, 75224, United States
Guangdong Provincial People's Hospital
RECRUITING

Guangzhou, 510080, China
Guys and St Thomas Hospital
RECRUITING

London, SE1 9RT, United Kingdom
Hallym University Sacred Heart Hospital
RECRUITING

Anyang-si, 14068, South Korea
Hirosaki University Hospital
RECRUITING

Aomori, 036-8563, Japan
Hiroshima University Hospital
RECRUITING

Hiroshima, 734-8551, Japan
Hokkaido University Hospital
RECRUITING

Hokkaido, 060-8648, Japan
Hope Clinic & Research Center
WITHDRAWN

Hialeah, Florida, 33010, United States
Hopital Bichat - Claude Bernard AP-HP
RECRUITING

Paris, 75877, France
Hopital Henri Mondor
RECRUITING

Créteil, 94000, France
Hopital Tenon
RECRUITING

Paris, 75020, France
Hospital Ampang
RECRUITING

Ampang, 68000, Malaysia
Hospital Do Rim E Hipertensao Fundacao Oswaldo Ramos
RECRUITING

São Paulo, São Paulo, 04038-002, Brazil
Hospital Kuala Lumpur
RECRUITING

Kuala Lumpur, FED. Territory of Kuala Lumpur, 50586, Malaysia
Hospital Ribera Polusa
RECRUITING

Lugo, 27004, Spain
Hospital Seri Manjung
RECRUITING

Seri Manjong, Pahang, 32040, Malaysia
Hospital Sibu
RECRUITING

Sibu, Sarawak, 96000, Malaysia
Hospital Tengku Ampuan Afzan
RECRUITING

Kuantan, Pahang, 25100, Malaysia
Hospital Universitari Arnau de Vilanova
RECRUITING

Lleida, Lerida, 25198, Spain
Hospital Universitario 12 De Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario La Paz - PPDS
RECRUITING

Madrid, 28046, Spain
Hospital Universitario Vall d'Hebron - PPDS
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Virgen del Rocio - PPDS
RECRUITING

Seville, 41013, Spain
Hospital de Clinicas de Porto Alegre HCPA PPDS
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hyogo Prefectural Nishinomiya Hospital
RECRUITING

Nishinomiya, 662-0918, Japan
Hôpital de Rangueil
RECRUITING

Toulouse, 31059, France
IRCCS Pavia - Istituti Clinici Scientifici Maugeri Spa ? Società Benefit
RECRUITING

Pavia, Lombardy, 27100, Italy
Instituto D?Or Pesquisa e Ensino - Hospital Gloria D?Or
RECRUITING

Rio de Janeiro, 22281, Brazil
Instituto Medico de la Fundacion Estudios Clinicos
RECRUITING

Rosario, S2013DTC, Argentina
Instituto Mexicano de Trasplantes
RECRUITING

Cuernavaca, Morelos, 62448, Mexico
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
RECRUITING

Barrio Belisario Domínguez Secc XVI, Mexico CITY (federal District), 14080, Mexico
Ippokratio General Hospital of Thessaloniki
WITHDRAWN

Thessaloniki, 546 42, Greece
Iwate Medical University Hospital
RECRUITING

Numakunai, 028-3695, Japan
Japanese Red Cross Fukuoka Hospital
RECRUITING

Fukuoka, 815-8555, Japan
Jichi Medical University Hospital
RECRUITING

Tochigi, 329-0498, Japan
Juntendo University Hospital
RECRUITING

Tokyo, 113-8431, Japan
Juntendo University Nerima Hospital, department of renal and hypertension
RECRUITING

Tokyo, 177-8521, Japan
Juntendo University Urayasu Hospital
RECRUITING

Chiba, 279-0021, Japan
Kanazawa Medical University Hospital
RECRUITING

Ishikawa, 920-0293, Japan
Kidney Disease Medical Group Inc-1505 Wilson Ter
RECRUITING

Glendale, California, 91206-4032, United States
Kidney and Hypertension Center
WITHDRAWN

Roseburg, Oregon, 97471, United States
Kings College Hospital
RECRUITING

London, SE5 9RS, United Kingdom
Klinikum Koln-Merheim
RECRUITING

Cologne, 51109, Germany
Konkuk University Medical Center
RECRUITING

Seoul, 05030, South Korea
Kumamoto University Hospital
RECRUITING

Kumamoto, 860-8556, Japan
Kyoto City Hospital
RECRUITING

Nakagyo-ku, 604-8845, Japan
L&C Professional Medical Research Institute
RECRUITING

West Miami, Florida, 33144, United States
LCC Medical Research - Miami - ClinEdge - PPDS
RECRUITING

Miami, Florida, 33126, United States
Leicester General Hospital
RECRUITING

Leicester, LE5 4PW, United Kingdom
Liverpool Hospital
RECRUITING

Liverpool, New South Wales, 2170, Australia
London Health Sciences Centre · Victoria Hospital
RECRUITING

London, Ontario, N6A 5W9, Canada
Los Angeles County Nephrology
RECRUITING

Montebello, California, 90640-2217, United States
Mackay Memorial Hospital-Taipei branch
RECRUITING

Zhongshan Dist., 10449, Taiwan
Massachussets General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Matsuyama Red Cross Hospital
RECRUITING

Ehime, 790-8524, Japan
Medizinische Hochschule Hannover
RECRUITING

Hanover, 30625, Germany
Milwaukee Nephrologists, Sc
WITHDRAWN

Wauwatosa, Wisconsin, 53226, United States
Miri Hospital
RECRUITING

Miri, 98000, Malaysia
Montreal General Hospital
RECRUITING

Montreal, Quebec, H3G 1A4, Canada
NYU Langone Nephrology Associates - Mineola
RECRUITING

Mineola, New York, 11501, United States
Nara Medical University Hospital
RECRUITING

Kashihara, 634-8522, Japan
Nara Prefecture General Medical Center
RECRUITING

Nara, 630-8054, Japan
National Hospital Organization Okayama Medical Center
RECRUITING

Okayama, 701-1192, Japan
National University Hospital
RECRUITING

Singapore, 119074, Singapore
Nepean Hospital
RECRUITING

Kingswood, New South Wales, 02747, Australia
Nephrologisches Zentrum Villingen-Schwenningen
RECRUITING

Villingen-Schwenningen, 78052, Germany
Nephrology Associates of Northern Illinois
RECRUITING

Hinsdale, Illinois, 60521, United States
Nephrology Associates of Northern Virginia Inc
RECRUITING

Fairfax, Virginia, 22033, United States
Ningbo No.2 Hospital
RECRUITING

Ningbo, 315000, China
North America Research Institute-San Dimas
RECRUITING

San Dimas, California, 91773, United States
North Carolina Nephrology, PA
RECRUITING

Raleigh, North Carolina, 27609, United States
Ohio State University Wexner Medical Center - Outpatient Care East
RECRUITING

Columbus, Ohio, 43203, United States
Okayama University Hospital
RECRUITING

Okayama-Shi Kita-Ku, 700-0914, Japan
Osaka University Hospital
RECRUITING

Suita, 565-0871, Japan
Ospedale Policlinico San Martino
RECRUITING

Genoa, Liguria, 16132, Italy
Ospedale San Giovanni Bosco
RECRUITING

Turin, Piedmont, 10154, Italy
Peking University First Hospital
RECRUITING

Beijing, 100034, China
Peking University People's Hospital
RECRUITING

Beijing, 100044, China
Pioneer Research Solutions
RECRUITING

Houston, Texas, 077099, United States
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia
Prolato Clinical Research Center
RECRUITING

Houston, Texas, 77054, United States
Queen Mary Hospital
RECRUITING

Hong Kong, 999077, Hong Kong
R & H Clinical Research
RECRUITING

Katy, Texas, 77449, United States
Renmin Hospital of Wuhan University
RECRUITING

Wuhan, 430060, China
Revival Research Institute - McKinney
RECRUITING

McKinney, Texas, 75071, United States
Robert-Bosch-Krankenhaus
RECRUITING

Stuttgart, 70376, Germany
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, SA5000, Australia
Royal Melbourne Hospital
RECRUITING

Parkville, Victoria, 3050, Australia
Ruijin Hospital Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, 200025, China
SCM Clinic - Prywatny Szpital Specjalistyczny
RECRUITING

Krakow, 31-559, Poland
SMG-SNU Boramae Medical Center
RECRUITING

Seoul, 156-707, South Korea
SPZOZ Centralny Szpital Klin
RECRUITING

Lodz, 92-213, Poland
Saitama Medical University Hospital
RECRUITING

Saitama, 350-0451, Japan
Salford Royal Hospital
RECRUITING

Salford, M6 8HD, United Kingdom
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Sanatorio Allende
RECRUITING

Córdoba, X5000JHQ, Argentina
Sanatorio Mayo Privado
RECRUITING

Córdoba, 5000, Argentina
Santa Casa de Misericordia de Belo Horizonte - PPDS
RECRUITING

Belo Horizonte, Minas Gerais, 30150-221, Brazil
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Shenzhen People's Hospital
RECRUITING

Shenzhen, 518020, China
Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital
RECRUITING

Chengdu, 610072, China
Sierra Nevada Nephrology Consultants
RECRUITING

Reno, Nevada, 89511, United States
Singapore General Hospital
RECRUITING

Singapore, 169608, Singapore
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
RECRUITING

Hangzhou, 310016, China
Soon Chun Hyang University Hospital Bucheon
RECRUITING

Bucheon-si, 420-767, South Korea
Southern California Medical Research Center
WITHDRAWN

La Palma, California, 90623, United States
St George Hospital
RECRUITING

Kogarah, New South Wales, 2217, Australia
St. Joseph-Krankenhaus
RECRUITING

Berlin, 12101, Germany
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
Sunrise Medical Management LLC
RECRUITING

Surprise, Arizona, 85374-8644, United States
Sunshine Hospital
RECRUITING

St Albans, Victoria, 3021, Australia
Szpital Kliniczny Dzieciatka Jezus
RECRUITING

Warsaw, 02-006, Poland
Szpital Kliniczny im. H.Swiecickiego UM w Poznaniu
RECRUITING

Późna, 60-355, Poland
Taichung Veterans General Hospital
RECRUITING

Xitun Dist., 40705, Taiwan
Taiping Hospital
RECRUITING

Taiping, Perak, 34000, Malaysia
Tan Tock Seng Hospital
RECRUITING

Singapore, 308433, Singapore
Texas Kidney Institute - Dallas
RECRUITING

Dallas, Texas, 75231, United States
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, 330000, China
The First Affiliated Hospital of Xian Jiao Tong University
RECRUITING

Xi'an, 710061, China
The First Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050031, China
The Jikei University Hospital
RECRUITING

Tokyo, 105-8471, Japan
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, 330008, China
The Second Affiliated Hospital of Nanjing Medical University
RECRUITING

Nanjing, 210003, China
The Second Affiliated Hospital of Soochow University
RECRUITING

Suzhou, 215004, China
The University of Hong Kong - Shenzhen Hospital
RECRUITING

Shenzhen, 518053, China
Tohoku University Hospital
RECRUITING

Miyagi, 980-8574, Japan
Tokushima University Hospital
RECRUITING

Tokushima, 770-8503, Japan
Tokyo Medical University Ibaraki Medical Center
RECRUITING

Inashiki-Gun, 300-0395, Japan
Tokyo Women's Medical University Hospital
RECRUITING

Tokyo, 162-8666, Japan
Tucson Neuroscience Research - M3 WR
WITHDRAWN

Tucson, Arizona, 85710, United States
UAB Nephrology Research Clinic
RECRUITING

Birmingham, Alabama, 35233, United States
Universitatsklinikum der RWTH Aachen
RECRUITING

Aachen, 52074, Germany
University General Hospital of Heraklion
RECRUITING

Heraklion, 71110, Greece
University General Hospital of Patras
RECRUITING

Pátrai, 265 04, Greece
University Malaya Medical Centre
RECRUITING

Kuala Lumpur, FED. Territory of Kuala Lumpur, 59100, Malaysia
University of California, Los Angeles (UCLA) - Hematology/Oncology Santa Monica
RECRUITING

Los Angeles, California, 90025-4837, United States
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
University of Mississippi Medical Center
RECRUITING

Jackson, Mississippi, 39216, United States
University of Tsukuba Hospital
RECRUITING

Tsukuba, 305-8576, Japan
University of Yamanashi Hospital
RECRUITING

Chūō, 409-3821, Japan
University of the Ryukyus Hospital
RECRUITING

Okinawa, 903-0125, Japan
Universitätsklinikum Leipzig
RECRUITING

Leipzig, Saxony, 04103, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
RECRUITING

Mainz, 55101, Germany
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza Radeckiego we Wroclawiu
RECRUITING

Wroc?aw, 50-556, Poland
Uniwersytecki Szpital Kliniczny w Opolu
RECRUITING

Opole, 45401, Poland
Utah Kidney Research Institute
RECRUITING

Salt Lake City, Utah, 84115, United States
Vancouver General Hospital
RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada
Venizeleio General Hospital of Heraklion
RECRUITING

Heraklion, 714 09, Greece
Virginia Commonwealth University
RECRUITING

Richmond, Virginia, 23298, United States
Vseobecna fakultni nemocnice v Praze
RECRUITING

Prague, 12808, Czechia
West China Hospital, Sichuan University
RECRUITING

Chengdu, 610041, China
Wuxi People's Hospital
RECRUITING

Wuxi, Jiangsu, 214023, China
Xinhua Hospital Affiliated To Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, China
Yamaguchi University Hospital
RECRUITING

Ube, 755-8505, Japan
Zhejiang Provincial People?s Hospital
RECRUITING

Hangzhou, 310014, China

Conditions

Explore the condition pages connected to this study.

PRIMARY IGA NEPHROPATHY