New drug hope for patients with advanced cancers

NCT ID NCT04145622

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called ifinatamab deruxtecan in people with advanced solid tumors that have not been cured by other treatments. The goal is to find the safest dose and see if the drug can shrink tumors. About 250 participants will take part, and those who benefit may continue treatment as long as it works and side effects are manageable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Aichi Cancer Center Hospital

    RECRUITING

    Aichi, 464-8681, Japan

  • Cancer Institute Hospital of JFCR

    RECRUITING

    Tokyo, 135-8550, Japan

  • Cedars-Sinai Medical Center- Samuel Oschin Comprehensive Cancer Institute

    WITHDRAWN

    Los Angeles, California, 90048, United States

  • Columbia University Medical Center

    WITHDRAWN

    New York, New York, 10032, United States

  • Dana Farber Cancer Institute

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02115, United States

  • Florida Cancer Specialists

    WITHDRAWN

    Orlando, Florida, 32804, United States

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Henry Ford Hospital

    ACTIVE_NOT_RECRUITING

    Detroit, Michigan, 48202, United States

  • Hokkaido University Hospital

    RECRUITING

    Hokkaido, 060-8648, Japan

  • John Theurer Cancer Center at Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Kagawa University Hospital

    RECRUITING

    Kagawa, 761-0793, Japan

  • Keio University Hospital

    RECRUITING

    Tokyo, 160-8582, Japan

  • Kindai University Hospital

    RECRUITING

    Ōsaka-sayama, 589-8511, Japan

  • Kobe City Medical Center General Hospital

    RECRUITING

    Hyōgo, 650-0047, Japan

  • MDACC (MD Anderson Cancer Center)

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • Memorial Sloan-Kettering Cancer Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065, United States

  • National Cancer Center Hospital

    RECRUITING

    Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Chiba, 277-8577, Japan

  • SCRI Oncology Partners

    ACTIVE_NOT_RECRUITING

    Nashville, Tennessee, 37203, United States

  • Saitama Cancer Center

    RECRUITING

    Saitama, 362-0806, Japan

  • Sarah Cannon Research Institute at HealthONE

    RECRUITING

    Denver, Colorado, 80218, United States

  • Shizuoka Cancer Center

    RECRUITING

    Shizuoka, 411-8777, Japan

  • Showa Medical University Hospital

    RECRUITING

    Tokyo, 142-8666, Japan

  • Sidney Kimmel Cancer Center - Thomas Jefferson

    WITHDRAWN

    Philadelphia, Pennsylvania, 19107, United States

  • Tennessee Oncology

    ACTIVE_NOT_RECRUITING

    Nashville, Tennessee, 37203, United States

  • The Ohio State University

    WITHDRAWN

    Columbus, Ohio, 43210, United States

  • The University of Osaka Hospital

    RECRUITING

    Osaka, 565-0871, Japan

  • Washington University

    ACTIVE_NOT_RECRUITING

    St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.