Heart drug hope for boys with duchenne

NCT ID NCT03340675

First seen Jan 30, 2026 · Last updated Apr 29, 2026 · Updated 10 times

Summary

This study tested an oral drug called ifetroban in 46 boys (ages 7 and up) with Duchenne muscular dystrophy (DMD). DMD is a genetic disease that weakens muscles, including the heart, and often leads to early death. The goal was to see if ifetroban is safe and can help control heart damage. Participants took the drug or a placebo for several weeks, and researchers monitored side effects and drug levels in the blood.

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Contacts and locations

Locations

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30341, United States

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Kennedy Krieger Institute

    Baltimore, Maryland, 21205, United States

  • Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

  • Mattel Children's Hospital

    Los Angeles, California, 90095, United States

  • Monroe Carrell Jr. Children's Hospital at Vanderbilt

    Nashville, Tennessee, 37232, United States

  • Riley Children's Hospital

    Indianapolis, Indiana, 46202, United States

  • Saint. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.