New drug targets heart failure in duchenne boys

NCT ID NCT03340675

First seen Jan 30, 2026 · Last updated May 15, 2026 · Updated 13 times

Summary

This study tested an oral drug called ifetroban in 46 males aged 7 and older with Duchenne muscular dystrophy (DMD) who also had heart problems. The goal was to see if the drug is safe and how it works in the body. DMD is a severe genetic disease that weakens muscles and often leads to deadly heart issues, and this research aimed to find a new treatment option.

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Contacts and locations

Locations

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30341, United States

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Kennedy Krieger Institute

    Baltimore, Maryland, 21205, United States

  • Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

  • Mattel Children's Hospital

    Los Angeles, California, 90095, United States

  • Monroe Carrell Jr. Children's Hospital at Vanderbilt

    Nashville, Tennessee, 37232, United States

  • Riley Children's Hospital

    Indianapolis, Indiana, 46202, United States

  • Saint. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.