New hope for duchenne hearts: experimental drug targets leading cause of death

NCT ID NCT03340675

Summary

This study tested ifetroban, an oral medication, to see if it could help control heart damage in boys and young men with Duchenne muscular dystrophy (DMD). Heart problems are now the leading cause of death for people with DMD. Forty-six participants took either the drug or a placebo daily for one year, with some continuing in an extended treatment phase. Researchers measured heart function, breathing, and quality of life to see if the treatment helped.

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Contacts and locations

Locations

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30341, United States

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Kennedy Krieger Institute

    Baltimore, Maryland, 21205, United States

  • Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

  • Mattel Children's Hospital

    Los Angeles, California, 90095, United States

  • Monroe Carrell Jr. Children's Hospital at Vanderbilt

    Nashville, Tennessee, 37232, United States

  • Riley Children's Hospital

    Indianapolis, Indiana, 46202, United States

  • Saint. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.