New hope for pancreatic cancer: tiny particles deliver Gene-Targeting therapy

NCT ID NCT03608631

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 24 times

Summary

This early-phase study tests a new treatment called iExosomes for people with metastatic pancreatic cancer that has a specific mutation in the KRAS gene (G12D). The treatment uses tiny particles from stem cells to deliver a molecule that blocks the mutated gene's activity. The study aims to find the best dose and check for side effects in about 28 participants whose cancer has worsened despite prior therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PANCREATIC DUCTAL ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.