New drug IDE574 enters human trials for Hard-to-Treat cancers

NCT ID NCT07540572

First seen Apr 30, 2026 · Last updated Jun 10, 2026 · Updated 8 times

Summary

This study tests a new drug called IDE574 in people with advanced solid tumors or a specific type of breast cancer (ER+, HER2-). The drug targets two enzymes that help cancer cells grow. The study has two parts: first, testing IDE574 alone in various cancers; second, combining it with another drug (fulvestrant) for breast cancer. About 160 participants will join to check safety, side effects, and whether the drug shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • NEXT Texas LLC - Austin

    RECRUITING

    Austin, Texas, 78758, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Texas LLC - Dallas

    RECRUITING

    Dallas, Texas, 75039, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Texas LLC - Houston

    RECRUITING

    Houston, Texas, 77054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Texas LLC - San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START Astera, LLC

    RECRUITING

    East Brunswick, New Jersey, 08816, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START Dallas Fort Worth, LLC

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START Mountain Region, LLC

    RECRUITING

    West Valley City, Utah, 84119, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START New York Long Island, LLC

    RECRUITING

    Lake Success, New York, 11042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Start San Antonio, LLC

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.