New drug IBI3014 enters first human tests for Hard-to-Treat cancers

NCT ID NCT06974812

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called IBI3014 in 250 adults with advanced solid tumors that cannot be removed by surgery. The drug is given by IV every 3 weeks at different doses. The main goals are to find the safest dose and to see if the drug can shrink tumors. This is the first time IBI3014 is being tested in humans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
IBI3014 (an experimental drug given by IV infusion every 3 weeks)
What this could lead to
If it works, this could point toward a new treatment option for people with advanced solid tumors that cannot be removed by surgery.
What could go wrong
This is a very early first-in-human study, so the drug may not shrink tumors or may cause unexpected side effects. Success in early phases does not guarantee later approval.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fujian cancer hospital

    RECRUITING

    Fuzhou, Fujian, 350014, China

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, 410000, China

  • Shanghai Pulmonary Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200433, China