New drug trial aims to tame debilitating autoimmune disease

NCT ID NCT05349214

Ongoing Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether a new drug called ianalumab can help control the disease and reduce symptoms for people with active Sjogren's syndrome. About 500 participants will receive injections of either the drug or a placebo for nearly a year to see if it safely lowers disease activity and improves dryness, pain, and fatigue. The goal is to see if this treatment can provide better long-term management of this chronic autoimmune condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advanced Medical Research

La Palma, California, 90623, United States
Advanced Rheumatology of Houston

Spring, Texas, 77382, United States
Arthritis Northwest PLLC

Spokane, Washington, 99204, United States
Arthritis Osteoporosis Assoc of NM

Las Cruces, New Mexico, 88011, United States
Arthritis and Osteoporosis

Charlotte, North Carolina, 28207, United States
Augusta University Georgia

Augusta, Georgia, 30912, United States
Bay Area Arthritis And Osteoporosis

Brandon, Florida, 33511, United States
Clin Invest Specialists Inc

Orland Park, Illinois, 60467, United States
Clinic of Robert Hozman

Skokie, Illinois, 60176, United States
Clinical Investigation Specialists, Inc.

Wauconda, Illinois, 60084, United States
First Outpatient Research Unit

San Antonio, Texas, 78229, United States
GNP Research

Cooper City, Florida, 33024, United States
North Georgia Rheumatology Group

Lawrenceville, Georgia, 30046, United States
Novartis Investigative Site

CABA, Buenos Aires, C1405BCH, Argentina
Novartis Investigative Site

Quilmes, Buenos Aires, 1878, Argentina
Novartis Investigative Site

San Miguel Tucuman, Tucumán Province, T4000DPK, Argentina
Novartis Investigative Site

Buenos Aires, 1646, Argentina
Novartis Investigative Site

Buenos Aires, C1055AAF, Argentina
Novartis Investigative Site

Buenos Aires, C1428DQG, Argentina
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Maroochydore, Queensland, 4558, Australia
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Woodville South, South Australia, 5011, Australia
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Hobart, Tasmania, 7000, Australia
Novartis Investigative Site

Salvador, Estado de Bahia, 40150 150, Brazil
Novartis Investigative Site

Curitiba, Paraná, 80030-110, Brazil
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São Paulo, São Paulo, 04266 010, Brazil
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Burgas, 8000, Bulgaria
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Plovdiv, 4002, Bulgaria
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Sofia, 1606, Bulgaria
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Vancouver, British Columbia, V5Z 1L7, Canada
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Sydney, Nova Scotia, B1P 1P3, Canada
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Toronto, Ontario, M5T 2S8, Canada
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Rimouski, Quebec, G5L 5T1, Canada
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Sherbrooke, Quebec, J1G 2E8, Canada
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Trois-Rivières, Quebec, G9A 3Y2, Canada
Novartis Investigative Site

Concepción, Bio Bio, 4070280, Chile
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Valdivia, Los Ríos Region, 5110683, Chile
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Santiago, RM, 7500588, Chile
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Hefei, Anhui, 230001, China
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Chongqing, Chongqing Municipality, 400010, China
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Nanjing, Jiangsu, 210008, China
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Nanchang, Jiangxi, 330006, China
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Pingxiang, Jiangxi, 337000, China
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Changchun, Jilin, 130021, China
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Taiyuan, Shanxi, 030001, China
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Chengdu, Sichuan, 610041, China
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Yinchuan, The Ningxia Hui Autonomous Reg, 750000, China
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Ürümqi, Xinjiang, 830001, China
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Hangzhou, Zhejiang, 310006, China
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Beijing, 100029, China
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Beijing, 100730, China
Novartis Investigative Site

Shanghai, 200011, China
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Shanghai, 200040, China
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Tianjin, 300052, China
Novartis Investigative Site

Xinxiang, 453099, China
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Medellín, Antioquia, 050001, Colombia
Novartis Investigative Site

Barranquilla, Atlántico, 080002, Colombia
Novartis Investigative Site

Bogota, Cundinamarca, 110221, Colombia
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Bucaramanga, Santander Department, 680003, Colombia
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Angers, 49933, France
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Brest, 29200, France
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Le Kremlin-Bicêtre, 94275, France
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Le Mans, 72000, France
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Strasbourg, 67000, France
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Cologne, North Rhine-Westphalia, 50937, Germany
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Dresden, Saxony, 01307, Germany
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Berlin, 13125, Germany
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Hanover, 30625, Germany
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Herne, 44649, Germany
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Athens, 115 21, Greece
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Athens, 115 27, Greece
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Székesfehérvár, Fejér, 8000, Hungary
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Debrecen, Hajdu Bihar Megye, 4032, Hungary
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Eger, 3300, Hungary
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Gyula, 5700, Hungary
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Szeged, 6725, Hungary
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Ahmedabad, Gujarat, 380013, India
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Ahmedabad, Gujarat, 380015, India
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Bangalore, Karnataka, 560 002, India
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Pune, Maharashtra, 411001, India
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New Delhi, 110029, India
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Kfar Saba, 4428164, Israel
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Ramat Gan, 5265601, Israel
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Ancona, AN, 60126, Italy
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Milan, MI, 20100, Italy
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Salerno, SA, 84131, Italy
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Udine, UD, 33100, Italy
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Naples, 80131, Italy
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Nagoya, Aichi-ken, 455-8530, Japan
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Nagoya, Aichi-ken, 4578510, Japan
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Nagoya, Aichi-ken, 4578511, Japan
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Kitakyushu, Fukuoka, 8078556, Japan
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Sapporo, Hokkaido, 0608543, Japan
Novartis Investigative Site

Sapporo, Hokkaido, 0608648, Japan
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Yokohama, Kanagawa, 2458575, Japan
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Kuwana, Mie-ken, 511-0061, Japan
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Sasebo, Nagasaki, 857-1195, Japan
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Kurashiki, Okayama-ken, 7100824, Japan
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Bunkyo Ku, Tokyo, 1138431, Japan
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Chuo Ku, Tokyo, 1048560, Japan
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Itabashi-ku, Tokyo, 1738610, Japan
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Meguro-ku, Tokyo, 152-8902, Japan
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Shinjuku-ku, Tokyo, 1608582, Japan
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Culiacán, Sinaloa, 80000, Mexico
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Mérida, Yucatán, 97070, Mexico
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México, 07029, Mexico
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Poznan, Greater Poland Voivodeship, 61-397, Poland
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Krakow, Lesser Poland Voivodeship, 30-727, Poland
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Wroclaw, Lower Silesian Voivodeship, 52-416, Poland
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Warsaw, 00-874, Poland
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Wroclaw, 50367, Poland
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Cluj-Napoca, Cluj, 400006, Romania
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Brasov, 500283, Romania
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Bucharest, 010825, Romania
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Bucharest, 011172, Romania
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Bratislava, 811 08, Slovakia
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Košice, 040 11, Slovakia
Novartis Investigative Site

Partizánske, 958 01, Slovakia
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Zvolen, 960 01, Slovakia
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Panorama, Western Cape, 7500, South Africa
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Stellenbosch, Western Cape, 7600, South Africa
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Santander, Cantabria, 39008, Spain
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Vigo, Pontevedra, 36214, Spain
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Barcelona, 08041, Spain
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Córdoba, 14004, Spain
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Madrid, 28009, Spain
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Valencia, 46026, Spain
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Stockholm, SE, 113 65, Sweden
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Kaohsiung City, 81346, Taiwan
Novartis Investigative Site

Kaohsiung City, 83301, Taiwan
Novartis Investigative Site

Taichung, 40447, Taiwan
Novartis Investigative Site

Taichung, 407219, Taiwan
Novartis Investigative Site

Doncaster, DN2 5LT, United Kingdom
Novartis Investigative Site

Leeds, LS1 3EX, United Kingdom
Novartis Investigative Site

Liverpool, L9 7AL, United Kingdom
Novartis Investigative Site

Newcastle upon Tyne, NE1 4LP, United Kingdom
Novartis Investigative Site

Swindon, SN3 6BB, United Kingdom
On Site Clinical Solutions Llc

Charlotte, North Carolina, 28202, United States
Prolato Clinical Research Center

Houston, Texas, 77054, United States
Providence Medical Foundation

Fullerton, California, 92835, United States
RAO Research LLC

Oklahoma City, Oklahoma, 73116, United States
Ramesh C Gupta MD Memphis TN

Memphis, Tennessee, 38119, United States
Sarasota Arthritis Res Ctr

Sarasota, Florida, 34239, United States
St Lawrence Health System

Potsdam, New York, 13676, United States
Tufts School of Dental Medicine

Boston, Massachusetts, 02111, United States
University of Kansas Hospital

Kansas City, Kansas, 66160, United States
West Tennessee Research Institute

Jackson, Tennessee, 38305, United States

Conditions

Explore the condition pages connected to this study.

SJOGREN SYNDROME