New drug trial targets Hard-to-Treat skin hardening disease

NCT ID NCT06470048

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called ianalumab to see if it can help control the progression of diffuse cutaneous systemic sclerosis, a severe form of scleroderma that causes skin thickening and can damage internal organs. About 200 adults with active, early-stage disease will receive either the drug or a placebo injection for one year, followed by an optional year of open-label treatment. Researchers will measure changes in skin thickness, lung function, and overall disability to determine if the treatment is effective and safe.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Arizona Arthritis and Rheumatology Research PLLC
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Mesa, Arizona, 85202, United States

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Arthritis and Rheumatology Ins
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Allen, Texas, 75013, United States

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Clinical Res Of W Florida
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Clearwater, Florida, 33765, United States

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Clinical Research Inst of MI
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Saint Clair Shores, Michigan, 48081, United States

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GNP Research
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Cooper City, Florida, 33024, United States

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Hoag Hospital
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Newport Beach, California, 92663, United States

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Hospital for Special Surgery
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New York, New York, 10021, United States

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IRIS Research and Development
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Plantation, Florida, 33324, United States

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Novartis Investigative Site
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CABA, Buenos Aires, 1280, Argentina
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CABA, Buenos Aires, C1221ADC, Argentina
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Caba, C1015ABO, Argentina
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Caba, C1426, Argentina
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San Miguel de Tucumán, 4000, Argentina
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Graz, 8036, Austria
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Leuven, 3000, Belgium
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Salvador, Estado de Bahia, 40150 150, Brazil
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Curitiba, Paraná, 80030-110, Brazil
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Porto Alegre, Rio Grande do Sul, 90035-074, Brazil
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Sao Jose Rio Preto, São Paulo, 15090 000, Brazil
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São Paulo, São Paulo, 04038-002, Brazil
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São Paulo, São Paulo, 05403-000, Brazil
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Nanning, Guangxi, 530021, China
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Zhengzhou, Henan, 450003, China
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Changchun, Jilin, 130021, China
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Chengdu, Sichuan, 610041, China
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Ningbo, Zhejiang, 315016, China
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Beijing, 100191, China
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Beijing, 100730, China
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Tianjin, 300052, China
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Medellín, Antioquia, 050001, Colombia
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Bogota, Cundinamarca, 110111, Colombia
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Bogota, Cundinamarca, 110221, Colombia
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Cali, Valle del Cauca Department, 760012, Colombia
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Bogotá, 110231, Colombia
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Medellín, 050034, Colombia
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Dijon, 21000, France
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Le Mans, 72000, France
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Lille, 59037, France
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Montpellier, 34295, France
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Paris, 75014, France
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Rennes, 35033, France
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Strasbourg, 67000, France
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Toulouse, 31054, France
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Würzburg, Bavaria, 97080, Germany
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Jena, Thuringia, 07740, Germany
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Berlin, 13353, Germany
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Alexandroupoli, 681 00, Greece
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Athens, 115 21, Greece
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Athens, 115 27, Greece
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Pécs, Baranya, 7623, Hungary
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Debrecen, Hajdu Bihar Megye, 4032, Hungary
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Budapest, H-1083, Hungary
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Kochi, Kerala, 682018, India
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Mumbai, Maharashtra, 400013, India
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Mumbai, Maharashtra, 400078, India
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New Delhi, National Capital Territory of Delhi, 110060, India
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Jaipur, Rajasthan, 302004, India
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New Delhi, 110029, India
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Ancona, AN, 60126, Italy
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Milan, MI, 20100, Italy
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Rozzano, MI, 20089, Italy
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Modena, MO, 41124, Italy
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Palermo, PA, 90127, Italy
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Pavia, PV, 27100, Italy
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Roma, RM, 00168, Italy
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Verona, VR, 37134, Italy
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Nagoya, Aichi-ken, 4578510, Japan
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Kitakyushu, Fukuoka, 8078556, Japan
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Maebashi, Gunma, 371 8511, Japan
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Sapporo, Hokkaido, 0608543, Japan
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Sapporo, Hokkaido, 0608648, Japan
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Kanazawa, Ishikawa-ken, 920 8641, Japan
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Yokohama, Kanagawa-ku, 236-0004, Japan
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Suita, Osaka, 5650871, Japan
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Iruma-gun, Saitama, 3500495, Japan
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Bunkyo-ku, Tokyo, 113-8603, Japan
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Chuo Ku, Tokyo, 1048560, Japan
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Shinjuku Ku, Tokyo, 1628666, Japan
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Shinjuku-ku, Tokyo, 1608582, Japan
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Fukuoka, 8128582, Japan
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Hiroshima, 7348551, Japan
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Kyoto, 6068507, Japan
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Toyama, 9300194, Japan
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Cheras, Kuala Lumpur, 56000, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Guadalajara, Jalisco, 44650, Mexico
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Mexico City, Mexico City, 06700, Mexico
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Mexico City, Mexico City, 11850, Mexico
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Monterrey, Nuevo León, 64460, Mexico
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Chihuahua City, 31000, Mexico
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Bydgoszcz, 85-168, Poland
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Warsaw, 00-874, Poland
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Coimbra, 3004-561, Portugal
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Lisbon, 1649-035, Portugal
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Vila Nova de Gaia, 4434 502, Portugal
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Seoul, Korea, 03080, South Korea
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Busan, 49241, South Korea
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Seoul, 04763, South Korea
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Seoul, 06273, South Korea
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Málaga, Andalusia, 29009, Spain
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Valencia, Valencia, 46017, Spain
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Barcelona, 08041, Spain
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Madrid, 28009, Spain
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Salamanca, 37007, Spain
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Changhua, 50006, Taiwan
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Kaohsiung City, 83301, Taiwan
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Taichung, 40447, Taiwan
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Taoyuan District, 33305, Taiwan
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Khon Kaen, THA, 40002, Thailand
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Bangkok, 10400, Thailand
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Istanbul, Fatih, 34093, Turkey (Türkiye)
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Ankara, Sihhiye-Altindag, 06230, Turkey (Türkiye)
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Ankara, Yenimahalle, 06500, Turkey (Türkiye)
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Basingstoke, Hampshire, RG24 9NA, United Kingdom
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Bristol, BS10 5NB, United Kingdom
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London, NW3 2QG, United Kingdom
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Ho Chi Minh City, VNM, 700000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
Novel Research LLC
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Bellaire, Texas, 77401, United States

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Prolato Clinical Research Center
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Houston, Texas, 77054, United States

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Sarasota Arthritis Res Ctr
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Sarasota, Florida, 34239, United States

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UCLA
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Los Angeles, California, 90095, United States

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UMC New Orleans
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New Orleans, Louisiana, 70112, United States

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Uni Of Michigan Health System
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Ann Arbor, Michigan, 48109, United States

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University of Chicago Hospitals
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Chicago, Illinois, 60637, United States

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Wayne State University
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Detroit, Michigan, 48201, United States

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West Tennessee Research Institute
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Jackson, Tennessee, 38305, United States

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Conditions

Explore the condition pages connected to this study.

DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS