New blood processing method could mean fewer transfusions for sickle cell patients
NCT ID NCT06743113
First seen Jan 10, 2026 · Last updated May 06, 2026 · Updated 15 times
Summary
This study tests whether red blood cells processed with the Hemanext ONE® system (hypoxic RBCs) last longer in the body compared to standard blood transfusions for people with sickle cell anemia. About 48 participants aged 7 and older who need regular transfusions will receive both types of blood in a crossover design. The goal is to see if hypoxic RBCs slow the decline of healthy hemoglobin, potentially reducing how often transfusions are needed.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Emory University School of Medicine
Atlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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John Hopkins University School of Medicine
Baltimore, Maryland, 21287, United States
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Johns Hopkins All Children's Hospital
St. Petersburg, Florida, 33701, United States
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New England Sickle Cell Institute, University of Connecticut
Farmington, Connecticut, 06030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15260, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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