Can a malaria drug help kids with a rare kidney disease?

NCT ID NCT04937907

First seen Mar 13, 2026 · Last updated May 13, 2026 · Updated 5 times

Summary

This study tested whether hydroxychloroquine, a drug used for malaria and autoimmune conditions, can reduce blood and protein in the urine of children with X-linked Alport syndrome, a genetic kidney disease. Fifty children aged 3-18 with stable kidney function took the drug for 48 weeks. The goal was to see if it could control kidney damage, not cure the disease.

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Contacts and locations

Locations

  • Shanghai Children's Hospital

    Shanghai, Shanghai Municipality, 200062, China

Conditions

Explore the condition pages connected to this study.