Could an old malaria drug help fight bone cancer?

NCT ID NCT03598595

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 26 times

Summary

This study tests a combination of two chemotherapy drugs (gemcitabine and docetaxel) plus hydroxychloroquine, a drug usually used for malaria, in people whose osteosarcoma has returned or stopped responding to standard treatments. The goal is to find the safest dose of hydroxychloroquine and see if the combination can control the cancer. About 31 participants will take part at M.D. Anderson Cancer Center.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.