New liver Drug's safety check: can it mix with hepatitis b antivirals?

NCT ID NCT07295873

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This early-stage trial will test a new drug called hydronidone, which is being developed for liver fibrosis caused by hepatitis B. Since patients often need to take antiviral drugs for hepatitis B, researchers want to see if hydronidone can be taken safely alongside four common antivirals. The study involves 64 healthy Chinese adults and will measure how the drugs interact in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hydronidone
What this could lead to
If successful, this study will show that hydronidone can be safely taken alongside common hepatitis B antivirals, paving the way for a combination treatment for liver fibrosis.
What could go wrong
This is an early Phase 1 trial in only 64 healthy people, not patients. It only checks drug interactions, not whether hydronidone actually treats liver fibrosis. Side effects may still emerge.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Gaobo Hospital

    Beijing, 100000, China

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Other studies related to the condition(s) this trial covers.