New device aims to calm bladder irritation during cancer therapy

NCT ID NCT06245603

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding Hydeal Cyst® instillations can reduce lower urinary tract symptoms in people receiving standard chemotherapy or immunotherapy for non-muscle invasive bladder cancer. About 200 participants will receive either BCG or MMC, and half will also get Hydeal Cyst®. The main goal is to see if symptoms improve, measured by a questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hydeal Cyst® (a device used as an intravesical instillation)

What this could lead to

If it works, this could provide a way to reduce urinary discomfort during standard bladder cancer therapy.

What could go wrong

This is an early-stage study with no phase designation, so results are uncertain. The device is tested alongside standard treatments, not as a replacement.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma Non-Muscle Invasive Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedale Università Padova

    RECRUITING

    Padova, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Universitaria Integrata - Verona

    RECRUITING

    Verona, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Humanitas Gavezzeni-Bergamo

    RECRUITING

    Bergamo, 24125, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto Oncologico Veneto IRCCS

    RECRUITING

    Padova, 35128, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Sant'Orsola - Malpighi

    NOT_YET_RECRUITING

    Bologna, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ospedale Santa Maria della Misericordia - ASU FC

    RECRUITING

    Udine, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ospedali Riuniti Padova Sud

    RECRUITING

    Padova, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Policlinico Ospedali Riuniti - Foggia

    RECRUITING

    Foggia, Italy

    Contact Email: •••••@•••••

    Contact

  • Policlinico Paolo Giaccone

    RECRUITING

    Palermo, 90127, Italy

    Contact Email: •••••@•••••