New Fat-Melting injection for double chin enters human testing

NCT ID NCT06756490

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests a new drug called HY-2003, a fat-dissolving injection for people with moderate to severe double chin. About 30 adults will receive either HY-2003, an existing treatment (BELKYRA), or a placebo. The main goal is to check safety, but researchers will also look at how well it reduces chin fat.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
liposome-encapsulated deoxycholic acid (HY-2003)
What this could lead to
If successful, this could offer a new injectable option for reducing double chin fat with potentially fewer side effects than current treatments.
What could go wrong
This is an early Phase 1 trial with only 30 participants, so safety and effectiveness are not yet proven. The treatment may cause injection-site reactions or fail to reduce fat better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100730, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    RECRUITING

    Xi'an, Shaanxi, 710061, China