Ancient herbal mix put to the test against IBS diarrhea
NCT ID NCT07721012
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether a traditional Chinese herbal formula called Huanghou Zhixie Diwan can reduce abdominal pain and diarrhea in people with irritable bowel syndrome (IBS-D). About 120 adults aged 18 to 65 who meet specific diagnostic criteria will receive either the herbal blend or a placebo for four weeks. The study aims to see if the formula provides meaningful symptom relief compared to a dummy pill.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a traditional Chinese herbal formula containing magnolia bark, coptis root, ginger oil, and costus root oil
- What this could lead to
- If effective, this herbal formula could offer a new option for managing IBS-related diarrhea and abdominal pain.
- What could go wrong
- This is an early phase 2 trial with only 120 participants, so results may not apply broadly. Herbal products can vary in potency and may cause side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Traditional Chinese Medicine Hospital, Capital Medical University
Beijing, China
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Daqing People's Hospital
Daqing, China
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GuangDong Second Traditional Chinese Medicine Hospital
Guangzhou, China
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Hebei Provincial Hospital of Traditional Chinese Medicine
Shijiazhuang, China
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Inner Mongolia Hospital of Traditional Chinese Medicine
Hohhot, China
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Lianyungang Hospital of Traditional Chinese Medicine
Lianyungang, China
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Luoyang First People's Hospital
Luoyang, China
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Luoyang Third People's Hospital
Luoyang, China
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Meihekou Central Hospital
Meihekou, China
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The First Hospital of Hunan University of Chinese Medicine
Changsha, China
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The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Tianjin, China
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The Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Shenyang, China
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Wenzhou TCM Hospital of Zhejiang Chinese Medical University
Wenzhou, China
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Xiamen Hospital of Traditional Chinese Medicine
Xiamen, China