New pill aims to ease stuffy noses and facial pain

NCT ID NCT07174115

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new tablet called HTMC0658 in 30 adults with chronic sinusitis (no nasal polyps). The goal is to see if it safely reduces symptoms like congestion, facial pain, and discharge over 12 weeks. Participants will have CT scans and symptom checkups to measure improvement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HTMC0658 tablet (also called YD0293)

What this could lead to

If successful, this could lead to a new oral treatment option for people with chronic sinusitis who don't have nasal polyps.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The drug may not improve symptoms or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC SINUSITIS WITHOUT NASAL POLYPS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Luoyang First People's Hospital

    RECRUITING

    Luoyang, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact