New pill aims to ease stuffy noses and facial pain
NCT ID NCT07174115
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new tablet called HTMC0658 in 30 adults with chronic sinusitis (no nasal polyps). The goal is to see if it safely reduces symptoms like congestion, facial pain, and discharge over 12 weeks. Participants will have CT scans and symptom checkups to measure improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HTMC0658 tablet (also called YD0293)
- What this could lead to
- If successful, this could lead to a new oral treatment option for people with chronic sinusitis who don't have nasal polyps.
- What could go wrong
- This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The drug may not improve symptoms or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Luoyang First People's Hospital
RECRUITINGLuoyang, Henan, China