New drug shows promise for slowing rare liver disease
NCT ID NCT03333928
Summary
This study tested whether a new oral drug called HTD1801 could help control primary sclerosing cholangitis (PSC), a rare disease that scars the bile ducts in the liver. For 18 weeks, 59 adult patients took either one of two doses of HTD1801 or a placebo pill. The main goal was to see if the drug could safely lower a key liver enzyme (ALP) in the blood, which is a sign of reduced liver damage.
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Contacts and locations
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Locations
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Arizona Liver Health
Chandler, Arizona, 85224, United States
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Arizona Liver Health
Tuscon, Arizona, 85711, United States
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Aspen Woods Clinic
Calgary, Alberta, T3H 0V5, Canada
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Cumberland Research Associates
Fayetteville, North Carolina, 28304, United States
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Florida Research Institute
Lakewood Rch, Florida, 34211, United States
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Fresno Clinical Research Center
Fresno, California, 93720, United States
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Gastro One
Germantown, Tennessee, 38138, United States
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Gastrointestinal Associates
Flowood, Mississippi, 39232, United States
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Keck School of Medicine of USC
Los Angeles, California, 90033, United States
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Mercy Medical Center
Baltimore, Maryland, 21202, United States
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Michigan Medicine University of Michigan
Ann Arbor, Michigan, 48109, United States
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Mount Sinai - Icahn School of Medicine
New York, New York, 10029, United States
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Pinnacle Clinical Research
Austin, Texas, 78746, United States
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Pinnacle Clinical Research
San Antonio, Texas, 78229, United States
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South Denver Gastroenterology, PC
Englewood, Colorado, 80113, United States
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Swedish Medical Center
Seattle, Washington, 98104, United States
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Toronto Centre for Liver Disease, Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
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University of Colorado, Denver
Aurora, Colorado, 80045, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Washington
Seattle, Washington, 98104, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37212, United States
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Wake Forest Baptist Health
Winston-Salem, North Carolina, 27157, United States
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Walter Reed National Military Medical Center
Bethesda, Maryland, 20889, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Yale School of Medicine
New Haven, Connecticut, 06520, United States
Conditions
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