New hope for kids with hard-to-treat brain tumors: experimental drug enters human testing

NCT ID NCT07158710

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests an experimental drug called HSK42360 in children aged 6 to 17 with a type of brain tumor that has a specific genetic change (BRAF V600 mutation) and has come back after standard treatment. The main goals are to find the safest dose and to see if the drug can shrink the tumors. About 159 children will take the drug by mouth, and researchers will monitor side effects and how well the drug works.

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Contacts and locations

Locations

  • Department of Neuro-oncology, Cancer Center, Beijing Tiantan Hospital, Capital Medical University,Beijing, China

    RECRUITING

    Beijing, Beijing Municipality, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fudan University Affiliated Huashan Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Third Bethune Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The first affiliated hospital of fujian medical university

    RECRUITING

    Fuzhou, Fujian, 350200, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xuanwu Hospital Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhujiang Hospital of Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510280, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.