Liver function may affect new PNH drug processing

NCT ID NCT07152288

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 33 times

Summary

This study looks at how the body processes a new drug called HSK39297 for paroxysmal nocturnal hemoglobinuria (PNH) in people with mild or moderate liver problems compared to those with healthy livers. About 24 adults will receive a single dose to measure drug levels and safety. The goal is to understand if liver impairment changes how the drug works, not to treat the disease directly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University First Hospital

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.