Liver function may affect new PNH drug levels

NCT ID NCT07152288

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 34 times

Summary

This study looks at how the body processes a new drug called HSK39297 for paroxysmal nocturnal hemoglobinuria (PNH) in people with mild or moderate liver problems compared to those with healthy livers. Researchers will measure drug levels in the blood and check for side effects after a single dose. The goal is to understand if liver health changes how the drug works, helping guide future dosing. 24 adults aged 18-70 are being recruited.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University First Hospital

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.