New drug HS-20110 enters human testing for Hard-to-Treat cancers
NCT ID NCT06892379
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This early-stage trial is testing a new drug called HS-20110 in 475 adults with advanced solid tumors that have not responded to standard treatments. The study aims to find a safe dose and see if the drug can shrink tumors. Participants receive HS-20110 by IV infusion in 21-day cycles.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- HS-20110
- What this could lead to
- If successful, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
- What could go wrong
- This is an early Phase 1 trial focused on safety and dosing, so it is too soon to know if HS-20110 will effectively shrink tumors. Side effects are unknown and could be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
BRCR Medical Center INC
RECRUITINGTamarac, Florida, 33321, United States
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Carolina BioOncology Institute
RECRUITINGHuntersville, North Carolina, 28078, United States
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Fort Wayne Medical Oncology and Hematology
RECRUITINGFort Wayne, Indiana, 46804, United States
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NEXT Dallas
RECRUITINGIrving, Texas, 75039, United States
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NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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SUN YAT-SEN University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510000, China
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can your own immune cells beat advanced cancer?
- Can a Dual-Pronged antibody outsmart advanced solid tumors?
- Can a new infusion drug shrink Hard-to-Treat tumors?
- Tumor DNA mapping may unlock personalized cancer therapies
- Can a new drug combo shrink Hard-to-Treat tumors?
- Can a protein calm the immune System's overreaction to cancer treatment?