New drug HS-20110 enters human testing for Hard-to-Treat cancers

NCT ID NCT06892379

First seen Feb 20, 2026 · Last updated Jun 23, 2026 · Updated 21 times

Summary

This early-stage trial is testing a new drug called HS-20110 in 475 adults with advanced solid tumors that have not responded to standard treatments. The study aims to find a safe dose and see if the drug can shrink tumors. Participants receive HS-20110 by IV infusion in 21-day cycles.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BRCR Medical Center INC

    RECRUITING

    Tamarac, Florida, 33321, United States

    Contact

  • Carolina BioOncology Institute

    RECRUITING

    Huntersville, North Carolina, 28078, United States

    Contact Phone: •••-•••-••••

    Contact

  • Fort Wayne Medical Oncology and Hematology

    RECRUITING

    Fort Wayne, Indiana, 46804, United States

    Contact

  • NEXT Dallas

    RECRUITING

    Irving, Texas, 75039, United States

    Contact

  • NEXT Oncology

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

  • SUN YAT-SEN University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510000, China

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HS-20110

What this could lead to

If successful, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.

What could go wrong

This is an early Phase 1 trial focused on safety and dosing, so it is too soon to know if HS-20110 will effectively shrink tumors. Side effects are unknown and could be serious.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.