New drug combo targets Hard-to-Treat prostate cancer
NCT ID NCT07115446
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial is testing two experimental drugs together in men with advanced prostate cancer that has worsened after standard hormone therapy. HS-20093 is an antibody-drug conjugate that targets a protein on cancer cells, while HRS-5041 is a drug that breaks down androgen receptors. The study will enroll 63 participants to find the safest dose and check for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HS-20093 (an antibody-drug conjugate) and HRS-5041 (a protein degrader targeting androgen receptors)
- What this could lead to
- If successful, this could point toward a new treatment option for men with advanced prostate cancer that has stopped responding to standard hormone therapy.
- What could go wrong
- This is an early phase 1 trial with only 63 participants, so it is primarily testing safety and dosing. The combination may not work well or could cause unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fudan University Shanghai Cancer Center
RECRUITINGShanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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