New pill aims to speed liver healing after cancer surgery

NCT ID NCT06638502

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests an experimental drug called HRX215 in people who had part of their liver removed because colon cancer spread there. The drug is meant to help the liver grow back and work better after surgery. About 80 adults will take either HRX215 or a placebo for 28 days, and researchers will check for side effects and measure liver regrowth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HRX215 capsules

What this could lead to

If it works, this could point toward a way to help the liver heal faster after surgery, reducing the risk of liver failure.

What could go wrong

This is a very early (Phase 1/2) trial with only 80 people, so it is not yet known if HRX215 is safe or effective. The drug may cause side effects or show no benefit over placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastasis from malignant tumor of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Régional Universitaire de Lille (CHRU) Hôpital Claude Huriez

    RECRUITING

    Lille, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Paul-Brousse - Centre Hepato-Biliaire (CHB)

    RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

  • Rabin Medical Center

    RECRUITING

    Petah Tikva, Israel

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • South Texas Accelerated Research Therapeutics Madrid - CIOCC - Universitario Sanchinarro

    NOT_YET_RECRUITING

    Madrid, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tel-Aviv Sourasky MC

    RECRUITING

    Tel Aviv, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Univ. Tuebingen - Universitaetsklinik fuer Allgemeine, Viszeral- und Transplantationschirurgie

    RECRUITING

    Tübingen, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••