New pill aims to speed liver healing after cancer surgery

NCT ID NCT06638502

Recruiting now Disease control Sponsor: HepaRegeniX GmbH Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 13, 2026 · Updated 8 times

Summary

This study tests an experimental drug called HRX215 in people who had part of their liver removed because colon cancer spread there. The drug is meant to help the liver grow back and work better after surgery. About 80 adults will take either HRX215 or a placebo for 28 days, and researchers will check for side effects and measure liver regrowth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: HRX215 capsules
What this could lead to: If it works, this could point toward a way to help the liver heal faster after surgery, reducing the risk of liver failure.
What could go wrong: This is a very early (Phase 1/2) trial with only 80 people, so it is not yet known if HRX215 is safe or effective. The drug may cause side effects or show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal carcinoma metastasis from malignant tumor of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CARCINOMA LIVER METASTASES COLORECTAL LIVER METASTASES LIVER RESECTION

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Centre Hospitalier Régional Universitaire de Lille (CHRU) Hôpital Claude Huriez
RECRUITING

Lille, France
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Consorci Hospital General Universitari de València
RECRUITING

Valencia, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, Spain
Hôpital Paul-Brousse - Centre Hepato-Biliaire (CHB)
RECRUITING

Villejuif, France
Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Rabin Medical Center
RECRUITING

Petah Tikva, Israel
Sheba Medical Center
RECRUITING

Ramat Gan, Israel
South Texas Accelerated Research Therapeutics Madrid - CIOCC - Universitario Sanchinarro
RECRUITING

Madrid, Spain
Tel-Aviv Sourasky MC
ACTIVE_NOT_RECRUITING

Tel Aviv, Israel
Univ. Tuebingen - Universitaetsklinik fuer Allgemeine, Viszeral- und Transplantationschirurgie
RECRUITING

Tübingen, Germany

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