New drug cocktail aims to tackle Hard-to-Treat breast cancer

NCT ID NCT06555068

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests an experimental drug called HRS-6209 in combination with several other breast cancer treatments (fulvestrant, letrozole, HRS-8080, or HRS-1358) for people with advanced breast cancer that cannot be surgically removed or has spread. The trial includes two stages: first finding a safe dose, then checking how well the combinations shrink tumors. Participants are women aged 18-75 whose cancer has not responded to standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called HRS-6209 combined with other breast cancer treatments
What this could lead to
If successful, this could provide a new treatment option for people with advanced breast cancer that has stopped responding to standard therapies.
What could go wrong
This is an early-phase trial, so the drug combination may not prove effective or could cause unexpected side effects. Results are preliminary and need confirmation in larger studies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact

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